Results 271 to 280 of about 499,256 (363)

Deciphering theBiological Decarboxylation Mechanismof Fatty Acids in Diiron Oxidative Decarboxylase UndA: Key Role ofthe Adaptive First Coordination Sphere

Ya-Ru Sheng (20296546), Chao Wang (146527), Hui Chen (28597)   +2 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

CPT1A inhibition alleviates plasmacytoid dendritic cell-mediated immune suppression in colon cancer through fatty acid oxidation modulation. [PDF]

J Immunother Cancer
Wu J, Zhu S, Zang G, Wang H, Yang N, Qiao Y, Wei Q, Wang L, Ren Z, Liu YJ, Chen J.   +10 more
europepmc   +1 more source

Skeletal muscle fuel utilisation in healthy and disregulated states [PDF]

, 2007
Wattis, Jonathan
core  

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Tissue specific roles of fatty acid oxidation. [PDF]

Adv Biol Regul
Smith DM, Choi J, Wolfgang MJ.
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Emerging roles for fatty acid oxidation in cancer. [PDF]

Genes Dis
Ma J, Wang S, Zhang P, Zheng S, Li X, Li J, Pei H.   +6 more
europepmc   +1 more source

Exercise alleviates diabetic kidney disease through PPARδ-CPT1α pathway-dependent fatty acid β-oxidation

Li Xiang, Li Wang, Yin Xia, Yu Wang, Jingchun Shi, Chenglin Zhang, Liping Xie, Yi Ru, Chak Kwong Cheng, Yujie Pu, Libing Hu, Junli Liu, Suowen Xu, Zongwei Cai, Yü Huang   +14 more
openalex   +2 more sources

Disorders of fatty acid transport and mitochondrial oxidation: Challenges and dilemmas of metabolic evaluation

, 2000
Piero Rinaldo, Dietrich Matern
openalex   +1 more source