Results 71 to 80 of about 496,965 (359)

HDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation

Journal of Lipid Research, 2018
Disregulation of fatty acid oxidation, one of the major mechanisms for maintaining hepatic lipid homeostasis under fasting conditions, leads to hepatic steatosis.
Xinchen Qiu, Jian Li, Sihan Lv, Jiamin Yu, Junkun Jiang, Jindong Yao, Yang Xiao, Bingxin Xu, Haiyan He, Fangfei Guo, Zhen-Ning Zhang, Chao Zhang, Bing Luan   +12 more
doaj   +1 more source

Regulation of peroxisomal fatty acid oxidation [PDF]

FEBS Letters, 1979
Isolated rat liver peroxisomes have been shown to P-oxidize fatty acids [ 1,2]. This activity is induced by some hypolidaemic drugs [3]. Peroxisomalfl-oxidation is also induced by di(2ethylhexyl)phthalate [4], and by high fat diets [5]. Most measurements of P-oxidation by isolated peroxisomal fractions have been carried out in grossly hypotonic media ...
Osmundsen, H., Neat, C.E.
openaire   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Mutations in the Arabidopsis Peroxisomal ABC Transporter COMATOSE Allow Differentiation between Multiple Functions In Planta: Insights from an Allelic Series [PDF]

, 2008
COMATOSE (CTS), the Arabidopsis homologue of human Adrenoleukodystrophy protein (ALDP), is required for import of substrates for peroxisomal β-oxidation.
Baker, A., Baldwin, J.M., Baldwin, S.A., Dietrich, D., Holdsworth, M.J., Lousa, C.D., Schmuths, H., Theodoulou, F.A.   +7 more
core   +4 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency [PDF]

, 2017
Acyl-CoA dehydrogenase 9 (ACAD9) is an assembly factor for mitochondrial respiratory chain Complex I (CI), and ACAD9 mutations are recognized as a frequent cause of CI deficiency.
Alharbi, Hana, Goetzman, Eric S., Haack, Tobias, Haberberger, Birgit, Häberle, Johannes, Karunanidhi, Anuradha, Kim, Jung-Ja, Mohsen, Al-Walid, Munnich, Arnold, Nicholls, Robert D., Prabhu, Dolly, Prochownik, Edward V., Prokisch, Holger, Rötig, Agnes, Schiff, Manuel, Taylor, Robert W., Uppala, Radha, Vockley, Jerry, Wang, Yudong, Xia, Chuanwu, Zhang, Yuxun   +20 more
core  

Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss [PDF]

, 2016
Excessive accumulation of fat as the result of more energy intake and less energy expenditure is known as obesity. Lipids are essential components in the human body and are vital for maintaining homeostasis and physiological as well as cellular ...
Mantso, Theodora, Panagiotidis, Mihalis, Rupasinghe, Vasantha, Sekhhon-Loodu, Satvir   +3 more
core   +1 more source

Liposomes enriched in oleic acid are less susceptible to oxidation and have less proinflammatory activity when exposed to oxidizing conditions

Journal of Lipid Research, 1998
As there is frequently a reciprocal relationship between oleic acid and linoleic acid content in LDL after dietary supplementation, it is difficult to determine the independent effects of oleic and linoleic acid on LDL oxidation.
Chris Lee, Joellen Barnett, Peter D. Reaven   +2 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Role of arginase 2 in systemic metabolic activity and adipose tissue fatty acid metabolism in diet-induced obese mice [PDF]

, 2019
Visceral adipose tissue (VAT) inflammation and metabolic dysregulation are key components of obesity-induced metabolic disease. Upregulated arginase, a ureahydrolase enzyme with two isoforms (A1-cytosolic and A2-mitochondrial), is implicated in ...
Atawia, Reem T, Benson, Tyler W, Caldwell, Robert W, Caldwell, Ruth B, Cutler, Christopher W, Meghil, Mohamed M, Toque, Haroldo A, Weintraub, Neal L, Yiew, Nicole K.H   +8 more
core   +2 more sources