Results 101 to 110 of about 1,202,863 (326)

Fatty acid activation in carcinogenesis and cancer development: Essential roles of long-chain acyl-CoA synthetases.

Oncology Letters, 2018
The significance of fatty acid metabolism in cancer initiation and development is increasingly accepted by scientists and the public due to the high prevalence of overweight and obese individuals.
Yue-qing Tang, Jing Zhou, S. Hooi, Yue-Ming Jiang, Guo-Dong Lu   +4 more
semanticscholar   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Effect of fertilization on the fat content and fatty acid profile of sorghum flour samples [PDF]

, 2018
In our experiments, changes in the fat content and fatty acid composition in the flour of sorghum cultivated in growing areas treated with different nitrogen fertilizer doses were studied by the gas chromatographic analysis of the fatty acid methyl ...
Bíró Attila, Diósi Gerda, Jevcsák Szintia, Jóvér János, Lehoczki Gábor, Murányi Eszter, Remenyik Judit, Sipos Péter   +7 more
core  

Candidate genes associated with fatty acid compositions in north American Atlantic salmon (Salmo salar)

BMC Genomics
Fatty acids are a requirement for normal development, however, since humans are unable to de novo produce essential fatty acids, they must be obtained from diet. Atlantic salmon is a major dietary source of nutritious and digestible fatty acids. Here, we
Barbara L. Langille, Manuel Juárez, Nuria Prieto, Solomon Boison, Panya Sae Lim, Bruce D. Swift, Amber F. Garber   +6 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

CHANGES IN PLASMA LIPID COMPOSITION IN PATIENTS WITH ESSENTIAL HYPERTENSION

Российский кардиологический журнал, 2003
To examine the relation between serum fatty acids, blood pressure and heart failure in hypertensive patients we conducted a study of 58 patients with essential hypertension (mean age 45,1 ± 9,4 years) and 22 healthy subjects.
A. V. Govorin, N. V. Lareva, B. S. Hyshiktuyev, A. P. Filev   +3 more
doaj  

Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids

BioMed Research International, 2017
Omega-3 fatty acids have proven to be very essential for human health due to their multiple health benefits. These essential fatty acids (EFAs) need to be uptaken through diet because they are unable to be produced by the human body.
Waleed Amjad Khan, Chun-Mei Hu, N. Khan, A. Iqbal, Shan-wu Lyu, F. Shah   +5 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Ácidos grasos esenciales en el perro (II) : aplicaciones clínicas [PDF]

, 1997
Este artículo de revisión hace referencia a las posibles aplicaciones clínicas de los ácidos grasos esenciales (AGE) en la medicina veterinaria. Se revisan tanto sus usos terapéuticos como profilácticos en diversas patologías y se pretenden explicar los ...
Baucells Sánchez, María Dolores, Crespo, N.   +1 more
core   +1 more source