Results 81 to 90 of about 349,684 (263)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Characterization of Three Types of Elongases from Different Fungi and Site-Directed Mutagenesis

Journal of Fungi
Fatty acid elongases play crucial roles in synthesizing long-chain polyunsaturated fatty acids. Identifying more efficient elongases is essential for enhancing oleaginous microorganisms to produce high yields of target products.
Yuxin Wang, Lulu Chang, Hao Zhang, Yong Q. Chen, Wei Chen, Haiqin Chen   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Importance of a balanced omega 6/omega 3 ratio for the maintenance of health: Nutritional recommendations

Nutrición Hospitalaria
The modification of dietary patterns has led to a change in fatty acid consumption, with an increase in the consumption of ω-6 fatty acids and a markerd reduction in the consumption of ω-3 fatty acids. This in turn has given rise to an imbalance in the ω-
C. Gómez Candela, L. M.ª Bermejo López, V. Loria Kohen   +2 more
doaj  

Seasonal variations in nutritional profile of the freshwater mud eel, Monopterus cuchia (Hamilton, 1822)

Journal of Fisheries, 2019
Seasonal variations of proximate compositions, amino acids, and fatty acids contents of Monopterus cuchia were studied for the first time in Bangladesh.
Sohel Rana, Md. Hasan Faruque, Md. Mostavi Enan Eshik, Md. Rakibul Hasan, Mohammad Shamsur Rahman   +4 more
doaj  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Comparative analysis of muscle nutritional composition in two indigenous fish species from Fuxian lake

Siliao yanjiu
The experiment aimed to evaluate the nutritional characteristics of two indigenous fish species in Fuxian lake. Selecting wild Anabarilius grahami, farmed Anabarilius grahami, and wild Acrossocheilus yunnanensis as research objects, the conventional ...
JIN Fangpeng, ZHOU Rui, ZHONG Wenwu, WU Junjie, LIU Zijun, HAO Junfeng, LENG Yun   +6 more
doaj  

Amino acid and fatty acid profiles of perennial Baki™ bean

Frontiers in Nutrition
To realize the potential of sainfoins to contribute to sustainable agriculture and expand on demonstrated uses and benefits, de novo domestication is occurring to develop perennial Baki™ bean, the trade name used by The Land Institute for pulses (i.e ...
Evan B. Craine, Spencer Barriball, Muhammet Şakiroğlu, Tessa Peters, Brandon Schlautman   +4 more
doaj   +1 more source