Results 31 to 40 of about 93,079 (252)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Genomic prediction and genetic parameter estimation for unsaturated and saturated fatty acids in Canadian dairy cattle

Scientific Reports
The current study aimed to obtain the estimates of heritabilities and genetic correlations and the prediction abilities and accuracy of Bayesian GBLUP and Bayesian alphabet (BayesA, BayesB, BayesC) models for total and individual monounsaturated ...
S. O. Peters, K. Kizilkaya, E. M. Ibeagha-Awemu, X. Zhao   +3 more
doaj   +1 more source

Identification of some uncommon monounsaturated fatty acids of bacteria [PDF]

Journal of Clinical Microbiology, 1992
Location of the double-bond position of monounsaturated fatty acids of various bacteria was accomplished with combined gas chromatography-mass spectrometry analysis of dimethyl disulfide (DMDS) derivatives. The monoenoic fatty acids from whole cells were converted to methyl esters and then to DMDS adducts and analyzed by capillary gas chromatography ...
C W, Moss, M I, Daneshvar
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Chemical Composition of Oils and Fats from Madagascar Cockroach (G. portentosa), Giant Cockroach (B. giganteus), and Mealworm (T. molitor)

Orbital: The Electronic Journal of Chemistry
This study aimed to extract oil and fat from three insect species: Gromphadorhina portentosa, Blaberus giganteus, and Tenebrio molitor, analyzing its fatty acid composition and antimicrobial potential.
João Víctor de Andrade dos Santos, Thiago Luis Aguayo de Castro, Claudia Andrea Lima Cardoso, Kelly Mari Pires de Oliveira, Ramon Santos de Minas, Samara de Almeida Oliveira, Gabriela dos Santos Talevi, Meline Neves Pinheiro, Marilene Rodrigues Chang, Daniele Cristina Vitorelli Venancio, Geilson Rodrigues da Silva, Angela Kwiatkowski   +11 more
doaj   +1 more source

Effect of Rolled or Extruded Flaxseeds in Finisher Diet on Pellet Quality, Performance, and n-3 Fatty Acids in Breast and Thigh Muscles of Broiler Chickens [PDF]

Poultry Science Journal, 2019
An experiment was conducted to compare the effect of corn-soybean meal finisher (29-42d) diets containing flaxseeds (rolled or extruded) on pellet quality, performance, n-3 fatty acids (FA) and oxidative stability of meat in broiler chickens.
Zhaleh S, Golian A, Zerehdaran S
doaj   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Effects on plasma lipoproteins of monounsaturated, saturated, and polyunsaturated fatty acids in the diet of African green monkeys

Journal of Lipid Research, 1990
Work by other investigators has shown that an increase in dietary content of monounsaturated fatty acids can result in a decreased plasma low density lipoprotein (LDL) cholesterol concentration.
LL Rudel, JL Haines, JK Sawyer
doaj   +1 more source

Development of real-time PCR assay for genotyping SNP rs41255693 in cattle SCD gene

AIMS Agriculture and Food, 2020
Increased content of monounsaturated fatty acids with low melting points in cattle milk and meat known to strongly affect their taste and nutritional value.
Svetlana N. Kovalchuk, Anna L. Arkhipova, Eugene A. Klimov   +2 more
doaj   +1 more source

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species [PDF]

Journal of Lipid Research, 2010
Enhanced production of monounsaturated fatty acids (FA) derived from carbohydrate-enriched diets has been implicated in the development of obesity and insulin resistance. The FA elongases Elovl-5 and Elovl-6 are regulated by nutrient and hormone status, and have been shown using intact yeast and mammalian microsome fractions to be involved in the ...
Green, Christopher D., Ozguden-Akkoc, Cansel G., Wang, Yun, Jump, Donald B., Olson, L. Karl   +4 more
openaire   +5 more sources