Results 31 to 40 of about 94,621 (264)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Genomic prediction and genetic parameter estimation for unsaturated and saturated fatty acids in Canadian dairy cattle

Scientific Reports
The current study aimed to obtain the estimates of heritabilities and genetic correlations and the prediction abilities and accuracy of Bayesian GBLUP and Bayesian alphabet (BayesA, BayesB, BayesC) models for total and individual monounsaturated ...
S. O. Peters, K. Kizilkaya, E. M. Ibeagha-Awemu, X. Zhao   +3 more
doaj   +1 more source

Extractable and lipopolysaccharide fatty acid and hydroxy acid profiles from Desulfovibrio species.

Journal of Lipid Research, 1985
An analysis of the phospholipid ester-linked and the lipopolysaccharide (LPS) fatty acids and hydroxy fatty acids of six lactate-utilizing Desulfovibrio-type sulfate-reducing bacteria (SRB) has been performed using capillary gas-liquid chromatography ...
A Edlund, P D Nichols, R Roffey, D C White   +3 more
doaj   +1 more source

Identification of some uncommon monounsaturated fatty acids of bacteria [PDF]

Journal of Clinical Microbiology, 1992
Location of the double-bond position of monounsaturated fatty acids of various bacteria was accomplished with combined gas chromatography-mass spectrometry analysis of dimethyl disulfide (DMDS) derivatives. The monoenoic fatty acids from whole cells were converted to methyl esters and then to DMDS adducts and analyzed by capillary gas chromatography ...
C W, Moss, M I, Daneshvar
openaire   +2 more sources

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

Advanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou, Peilong Lai, Guanjie Peng, Bo Lu, Lizhen Jiang, Xinyue Li, Jinghong Chen, Ladi Mo, Qiong Mao, Haichuan Zhang, Jinxin Fang, Yi Meng, Aochu Liu, Yingyin Gao, Andong Huang, Wenhui Lin, Shiwen Hu, Zerong Guan, Xiaolan Ye, Zhenguo Liu, Liling Jiang, Yueyuan Zheng, Xianping Shi   +22 more
wiley   +1 more source

Chemical Composition of Oils and Fats from Madagascar Cockroach (G. portentosa), Giant Cockroach (B. giganteus), and Mealworm (T. molitor)

Orbital: The Electronic Journal of Chemistry
This study aimed to extract oil and fat from three insect species: Gromphadorhina portentosa, Blaberus giganteus, and Tenebrio molitor, analyzing its fatty acid composition and antimicrobial potential.
João Víctor de Andrade dos Santos, Thiago Luis Aguayo de Castro, Claudia Andrea Lima Cardoso, Kelly Mari Pires de Oliveira, Ramon Santos de Minas, Samara de Almeida Oliveira, Gabriela dos Santos Talevi, Meline Neves Pinheiro, Marilene Rodrigues Chang, Daniele Cristina Vitorelli Venancio, Geilson Rodrigues da Silva, Angela Kwiatkowski   +11 more
doaj   +1 more source

Effect of Rolled or Extruded Flaxseeds in Finisher Diet on Pellet Quality, Performance, and n-3 Fatty Acids in Breast and Thigh Muscles of Broiler Chickens [PDF]

Poultry Science Journal, 2019
An experiment was conducted to compare the effect of corn-soybean meal finisher (29-42d) diets containing flaxseeds (rolled or extruded) on pellet quality, performance, n-3 fatty acids (FA) and oxidative stability of meat in broiler chickens.
Zhaleh S, Golian A, Zerehdaran S
doaj   +1 more source

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier, Mayher Kaur, Milena Chaufan, Felix‐Levin Hormann, Luiza Martins Nascentes Melo, Mario Palma, Jordan Torpey, Yanshan Liang, Alanis Carmona, Cameron Fraser, Midori Flores, Krystina J. Szylo, Mahsa Yavari, Sheng Hui, Alpaslan Tasdogan, Sven Heiles, Jessalyn M. Ubellacker   +16 more
wiley   +1 more source

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species [PDF]

Journal of Lipid Research, 2010
Enhanced production of monounsaturated fatty acids (FA) derived from carbohydrate-enriched diets has been implicated in the development of obesity and insulin resistance. The FA elongases Elovl-5 and Elovl-6 are regulated by nutrient and hormone status, and have been shown using intact yeast and mammalian microsome fractions to be involved in the ...
Green, Christopher D., Ozguden-Akkoc, Cansel G., Wang, Yun, Jump, Donald B., Olson, L. Karl   +4 more
openaire   +5 more sources

Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation

Advanced Science, EarlyView.
The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley   +1 more source