Results 51 to 60 of about 1,225,208 (304)

Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity. [PDF]

PLoS ONE, 2017
BACKGROUND AND AIM:Fatty acids acutely stimulate GLP-1 secretion from L-cells in vivo. However, a high fat diet has been shown to reduce the density of L-cells in the mouse intestine and a positive correlation has been indicated between L-cell number and
Ketan Thombare, Stelia Ntika, Xuan Wang, Camilla Krizhanovskii   +3 more
doaj   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Unsaturated Fatty Acids and Their Immunomodulatory Properties

Biology, 2023
Oils are an essential part of the human diet and are primarily derived from plant (or sometimes fish) sources. Several of them exhibit anti-inflammatory properties. Specific diets, such as Mediterranean diet, that are high in ω-3 polyunsaturated fatty acids (PUFAs) and ω-9 monounsaturated fatty acids (MUFAs) have even been shown to exert an overall ...
Salvatore Coniglio, Maria Shumskaya, Evros Vassiliou   +2 more
openaire   +3 more sources

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source

Effect of maturation degree on fatty acid profile of different tissues in wild and farmed rohu (Labeo rohita)

Grasas y Aceites, 2011
During the breeding season, lots of physiological changes occur in the bodies of fish which lead to other phenotypical, anatomical and behavioral changes.
Bilal Hussain, Shahid Mahboob, Muhammad Hassan, Shahid Nadeem, Tayyaba Sultana   +4 more
doaj   +1 more source

Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host -- parasite interactions [PDF]

, 2013
Interactions between hosts and parasites can be substantially modulated by host nutrition. Polyunsaturated fatty acids (PUFAs) are essential dietary nutrients; they are indispensable as structural components of cell membranes and as precursors for ...
Ebert, Dieter, Dieter Ebert, Dominik Martin-Creuzburg, Martin-Creuzburg, Dominik, Nina Schlotz, Schlotz, Nina   +5 more
core   +1 more source

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

Advanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang, Hongyue Ma, Feier Bai, Jing Zhang, Yan Qi, Bing Shao   +5 more
wiley   +1 more source

Seasonal changes of fatty acids in Nerita textiles on intertidal area of Chabahar Bay (Oman Sea)

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2012
The aim of this research was to identify and isolate the fatty acids composition of Nerita textiles in intertidal area of Chabahar Bay, and also to explore the seasonal changes of fatty acid content in Nerita textiles.
N. Sajjadi email ; P. Eghtesadi; K. Darvish Bastami
doaj  

Impact of feeding by Arenicola marina (L.) and ageing of faecal material on fatty acid distribution and bacterial community structure in marine sediments: An experimental approach [PDF]

, 2006
The fate of ingested eukaryotic photoautotrophic fatty acids during gut transit in the lugwormArenicolamarina (L.) and the influence of A. marina's faeces on the evolution of fatty acid distribution and bacterial community structure in superficial ...
Caradec, S, Cuny, P, Nerini, David, Nerini, D, Gilbert, F, Cuny, Philippe, Caradec, Sarah, Gilbert, Franck, Pancost, Richard, Grossi, Vincent, Grossi, V, Pancost, RD   +11 more
core   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source