Results 51 to 60 of about 209,045 (310)
Advanced Science, EarlyView.The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
Effect of gamma irradiation on fatty acid composition of rainbow trout (Oncorhynchus mykiss) fillets [PDF]
, 2011 The present study was conducted to evaluate the effect of low-dose gamma irradiation (0, 1, 3 and 5 kGy) on fatty acid composition of Rainbow trout (Oncorhynchus mykiss) fillet. Among all of the fatty acids, oleic acid (C18:1) (with mean 33.50±3.02 g/100
Hemmasi, A.H. +4 more
core
Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans [PDF]
, 2014 Peer reviewedPublisher ...
Cowen, Leah E., Leach, Michelle D.
core +1 more source
Unsaturated fatty acids induce non‐canonical autophagy [PDF]
The EMBO Journal, 2015 To obtain mechanistic insights into the cross talk between lipolysis and autophagy, two key metabolic responses to starvation, we screened the autophagy-inducing potential of a panel of fatty acids in human cancer cells. Both saturated and unsaturated fatty acids such as palmitate and oleate, respectively, triggered autophagy, but the underlying ...
Niso Santano, Mireia +26 more
openaire +5 more sources
Advanced Science, EarlyView.We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Dietary unsaturated fatty acids affect the mammary gland integrity and health in lactating dairy cows [PDF]
, 2011 Background Information about the effects of unsaturated fatty acids (UFA) supplementation on the health and integrity of the mammary gland in lactating dairy cows is lacking.
Baal, J., van +4 more
core +2 more sources
Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics. [PDF]
PLoS ONE, 2008 BACKGROUND: The effect of dietary fats on human health and disease are likely mediated by changes in gene expression. Several transcription factors have been shown to respond to fatty acids, including SREBP-1c, NF-kappaB, RXRs, LXRs, FXR, HNF4alpha, and ...
Linda M Sanderson +6 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Nitro-fatty acid formation and metabolism [PDF]
, 2018 Nitro-fatty acids (NO 2 -FA) are pleiotropic modulators of redox signaling pathways. Their effects on inflammatory signaling have been studied in great detail in cell, animal and clinical models primarily using exogenously administered nitro-oleic acid ...
Bonacci, Gustavo Roberto +4 more
core +1 more source
Horticulturae, 2022 The present research intents to study skin fatty acids and physiological disorders developed during cold storage in ‘Golden Delicious’ apples treated with 1-MCP and calcium.
Maria Dulce Antunes +6 more
doaj +1 more source