Results 81 to 90 of about 809,717 (317)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Seasonal changes of fatty acids in Nerita textiles on intertidal area of Chabahar Bay (Oman Sea)

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2012
The aim of this research was to identify and isolate the fatty acids composition of Nerita textiles in intertidal area of Chabahar Bay, and also to explore the seasonal changes of fatty acid content in Nerita textiles.
N. Sajjadi email ; P. Eghtesadi; K. Darvish Bastami
doaj  

Is There a Fatty Acid Taste? [PDF]

Annual Review of Nutrition, 2009
Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clearly contributes sensory properties ...
openaire   +2 more sources

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism

, 1992
Eicosanoids, in particular prostaglandin E2 (PGE2), are potent inhibitors of a number of immune responses, including lymphocyte proliferation. We have previously shown that fatty acids, especially polyunsaturated fatty acids (PUFA), inhibit mitogen ...
Calder, P.C., Newsholme, E.A., Bevan, S.J.   +2 more
core  

Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia [PDF]

, 2012
The biomarker "ischemia-modified albumin" (IMA), measured by the albumin-cobalt-binding assay (ACB assay), is the only FDA-approved biomarker for early diagnosis of myocardial ischemia.
Peter J. Sadler, Sadler, P. J., Sadler, Peter J., Claudia A. Blindauer, Teresa J. T. Pinheiro, Stewart, Alan J., Blindauer, Claudia A., Pinheiro, Teresa J. T., Jin Lu, Lu, Jin, Alan J. Stewart   +10 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Evaluation of Types and Amounts of Fatty Acid Content in some most Consumed Iranian Fast Foods

مجله دانشکده پزشکی اصفهان, 2009
Background:There is an important concern about the intake of foods which contains trans fatty acids due to their harmful effects on human health. Although adverse affects of trans fatty acids on the cardiovascular system were established, but a few data ...
Bahar Nazari, Seddigeh Asgary, Nizal Sarrafzadegan, Salbali Saberi, Leila Azadbakht, Ahmad Esmaillzadeh   +5 more
doaj  

Sex-specific effect of dietary fatty acids on non-alcoholic fatty liver disease

Frontiers in Nutrition
BackgroundNon-alcoholic fatty liver disease is the most common chronic hepatic disease worldwide. Dietary fatty acid is tightly associated with the development of non-alcoholic fatty liver disease but few large-scale and in-depth clinical researches have
Jianhua Chen, Zeqin Zhang, Yuning Pan, Jiejun Shi   +3 more
doaj   +1 more source

Dietary cyclic fatty acids derived from linolenic acid do not exhibit intrinsic toxicity in the rat during gestation

Animal, 2008
Heating oils and fats may lead to cyclization of polyunsaturated fatty acids, especially those showing multiple double bonds like linolenic acid. Cyclohexenyl and cyclopentenyl fatty acids are subsequently present in some edible oils and these were ...
L. Bretillon, A. Roy, B. Pasquis, J.-L. Sébédio   +3 more
doaj   +1 more source