Results 21 to 30 of about 1,719,926 (258)

Improving the accuracy of fatty liver index to reflect liver fat content with predictive regression modelling [PDF]

open access: yes, 2022
The fatty liver index (FLI) is frequently used as a non-invasive clinical marker for research, prognostic and diagnostic purposes. It is also used to stratify individuals with hepatic steatosis such as non-alcoholic fatty liver disease (NAFLD), and to ...
Whitcher, B.   +5 more
core   +1 more source

Fatty liver incidence and predictive variables. [PDF]

open access: yes, 2010
Although fatty liver predicts ischemic heart disease, the incidence and predictors of fatty liver need examination. The objective of this study was to determine fatty liver incidence and predictive variables.
Akahoshi, Masazumi   +17 more
core   +1 more source

GSH Attenuates Organ Injury and Improves Function after Transplantation of Fatty Livers [PDF]

open access: yes, 2010
Ischemia-reperfusion injury (IRI) is increased after transplantation of steatotic livers. Since those livers are increasingly used for transplantation, protective strategies must be developed. Reactive oxygen species (ROS) play a key role in hepatic IRI.
Jauch, Karl-Walter   +15 more
core   +1 more source

Growth inhibition and morphologic changes of HeLa cells exposed to unsaturated fatty acid fraction from the liver of x-ray irradiated rabbits (OX) [PDF]

open access: yes, 1962
Biological effect of the unsaturated fatty acid fraction from the X-ray irradiated rabbit liver (OX) on HeLa cells has been observed in vitro comparing with the effect displayed on the same strain cells by the unsaturated fatty acid fraction from the non-
Yamamoto, Michio   +2 more
core   +1 more source

Non-alcoholic fatty liver disease: a global concern

open access: yes, 2022
Liver disease is a worldwide issue with death rates exponentially increasing over the last 50 years. Although there are many underlying aetiologies, one of the top three causes of liver disease is non-alcoholic fatty liver disease (NAFLD), which is an ...
Mortimore, G.
core   +1 more source

Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in HumansSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: OATP1B3/SLCO1B3 is a human liver-specific transporter for the clearance of endogenous compounds (eg, bile acid [BA]) and xenobiotics.
Qiong Pan   +16 more
doaj   +1 more source

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]

open access: yes, 2011
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar   +21 more
core   +1 more source

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]

open access: yes, 2011
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...
Palmer Cameron D.   +799 more
core   +3 more sources

Hepatic Aquaporin 10 Expression Is Downregulated by Activated NFκB Signaling in Human Obstructive Cholestasis

open access: yesGastro Hep Advances, 2023
Background and Aims: Recent studies reported that the hepatic expression of AQP8 and AQP9 was downregulated in bile duct-ligated (BDL) rats and that overexpression of human AQP1 in the rat liver attenuated cholestasis.
Min Liao   +10 more
doaj   +1 more source

A "systems medicine" approach to the study of non-alcoholic fatty liver disease

open access: yes, 2015
The prevalence of fatty liver (steatosis) in the general population is rapidly increasing worldwide. The progress of knowledge in the physiopathology of fatty liver is based on the systems biology approach to studying the complex interactions among ...
Grieco, Antonio
core   +1 more source

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