Results 71 to 80 of about 2,963,117 (406)
BMJ Open, 2021 Objective To give a comprehensive efficacy and safety ranking of different therapeutic regimens of ranibizumab for neovascular age-related macular degeneration (nAMD).Design A systematic review and network meta-analysis.Methods The PubMed, Embase ...
Youxin Chen, Xinyu Zhao, Lihui Meng
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Melatonin attenuates cholestatic liver injury by improving bile acid metabolism in mice
陆军军医大学学报Objective To explore the mechanism of melatonin (Mel) alleviating cholestatic liver injury in a mouse cholestasis model induced by cholic acid (CA) feeding.
ZHANG Hongjia, TAN Ya, ZHAO Nan
doaj +1 more source
Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]
, 2019 Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Breaban, Iulia +10 more
core +1 more source
The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease [PDF]
, 2017 Objectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor.
Babraj, John A. +3 more
core +5 more sources
Nonalcoholic fatty liver disease [PDF]
Canadian Medical Association Journal, 2005 Nonalcoholic fatty liver disease is emerging as the most common chronic liver condition in the Western world. It is associated with insulin resistance and frequently occurs with features of the metabolic syndrome. Disease presentation ranges from asymptomatic elevated liver enzyme levels to cirrhosis with complications of liver failure and ...
Leon A, Adams +2 more
openaire +3 more sources
Hepatology, 2017 Nonalcoholic fatty liver disease (NAFLD) and resulting nonalcoholic steatohepatitis (NASH) are highly prevalent in the United States, where they are a growing cause of cirrhosis and hepatocellular carcinoma (HCC) and increasingly an indicator for liver ...
C. Estes +4 more
semanticscholar +1 more source
KASL clinical practice guidelines: Management of nonalcoholic fatty liver disease
Clinical and Molecular Hepatology, 2021 AGREE II, Appraisal of Guidelines for Research and Evaluation II; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUC, area under the receiver operating characteristic curve; BMI, body mass index; CAP, controlled attenuation parameter ...
S. Kang +19 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Pathomechanism of Insulin Resistance in Men with Central Obesity: Correlation of GGT, GPx, Hs-CRP and Plasma Total Cysteine [PDF]
, 2013 BACKGROUND: Gamma glutamyltransferase (GGT) was reported recently to be associated with inflammation, oxidative stress and increased amino acid. However, role of GGT in insulin resistance pathomechanism is not exactly known.
Patellongi, I. (Ilhamjaya) +3 more
core +4 more sources