Results 41 to 50 of about 6,127,399 (262)

Non-alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes

, 2013
BackgroundThe relationship between non-alcoholic fatty liver disease (NAFLD) and atrial fibrillation (AF) in type 2 diabetes is currently unknown. We examined the relationship between NAFLD and risk of incident AF in people with type 2 diabetes.Methods ...
Zoppini Giacomo, S. Rodella, Filippo Valbusa, Mantovani William, Mantovani, W., BARBIERI, Enrico, Bertolini Lorenzo, ZOPPINI, Giacomo, L. Zenari, Byrne Christopher D., Zoppini, G., Giacomo Zoppini, Stefano Bonapace, Byrne, Christopher D., Stefano Rodella, Bertolini, L., CD Byrne, Bonapace Stefano, Giovanni Targher, L. Bertolini, Targher, G., Bonapace, S., Valbusa, F., Targher Giovanni, Christopher D Byrne, TARGHER, Giovanni, F. Valbusa, Barbieri, E., MANTOVANI, William, Barbieri Enrico, Rodella, S., Enrico Barbieri, Valbusa Filippo, Luciano Zenari, Zenari, L., William Mantovani, Rodella Stefano, Lorenzo Bertolini, Zenari Luciano, S. Bonapace   +39 more
core   +1 more source

Evaluating large language models' performance in answering common questions on drug-induced liver injury

JHEP Reports
Background & Aims: Drug-induced liver injury (DILI) is a complex condition often linked to medication behaviors, with patient education having a crucial role in optimizing outcomes.
Yinuo Dong, Zili Zhang, Yang Zhi, Xiaoyun Li, Tengyu Guo, Lanlan He, Shuran Zhao, Xueli Yang, Jieting Tang, Wei Zhong, Qinghui Niu, Mingyang Ma, Zuxiong Huang, Yimin Mao   +13 more
doaj   +1 more source

Fatty liver with metabolic disorder, such as metabolic dysfunction‐associated fatty liver disease, indicates high risk for developing diabetes mellitus

Journal of Diabetes Investigation, 2022
Introduction Nonalcoholic fatty liver disease (NAFLD) is diagnosed after excluding other liver diseases. The pathogenesis of NAFLD when complicated by other liver diseases has not been established completely.
Teruki Miyake, Bunzo Matsuura, Shinya Furukawa, Toru Ishihara, Osamu Yoshida, Masumi Miyazaki, Kyoko Watanebe, Akihito Shiomi, Hironobu Nakaguchi, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Eiji Takeshita, Teru Kumagi, Masanori Abe, Yoshio Ikeda, Takeru Iwata, Yoichi Hiasa   +18 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Fatty liver syndrome in captive bustards: Clinical, pathological and epidemiological findings [PDF]

, 1997
Clinical, pathological, and epidemiological findings are presented on fatty liver syndrome mainly in houbara bustards (Chlamydotis undulata macqueenii), but also in some other bustard species.
Nicholls, P.K., Bailey, T.A., Samour, J.A.   +2 more
core  

Association between the gut microbiota and nonalcoholic fatty liver disease: A two-sample Mendelian randomization study

, 2023
BACKGROUND: Increasing studies have shown that there is a significant association between gut microbiota and non-alcoholic fatty liver disease. AIMS: To show the potential association between gut microbiota and non-alcoholic fatty liver disease, we ...
Li, Yu, Wang, Y, Liang, Xifeng, Han, L, Yuhan Wang, Liang, X, Chi, Cheng, Sun, J, Jing Sun, Yaning Lyu, Lyu, Y, Cheng Chi, Wang, K, Chi, C, Wang, Yuhan, Li, Y, Xifeng Liang, Linjing Han, Yu Li, Kexue Wang, Sun, Jing, Han, Linjing, Wang, Kexue, Lyu, Yaning   +23 more
core   +1 more source

Association between eGDR and MASLD and liver fibrosis: a cross-sectional study based on NHANES 2017–2023

Frontiers in Medicine
BackgroundThis study aimed to investigate the association between estimated glucose disposal rate (eGDR) and metabolic dysfunction-associated steatotic liver disease (MASLD), as well as liver fibrosis, using data from the National Health and Nutrition ...
Wenjing Peng, Zeyu Li, Nian Fu
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Molecular mechanisms of insulin resistance in chronic liver disease [PDF]

, 2008
The work presented here analyses the role of PP2A in the dysregulation of glucose metabolism in the setting of chronic hepatitis C. We propose a new model for virus induced insulin resistance development through the overexpression of PP2A in the liver ...
Bernsmeier, Christine
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source