Results 51 to 60 of about 11,419,856 (305)

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Software-based fault-tolerant routing algorithm in multidimensional networks [PDF]

, 2006
Massively parallel computing systems are being built with hundreds or thousands of components such as nodes, links, memories, and connectors. The failure of a component in such systems will not only reduce the computational power but also alter the ...
Ould-Khaoua, M., N. Alzeidi, M. Rezazad, Alzeidi, N., Rezazad, M., M. Fathy, F. Safaei, A. Khonsari, Safaei, F., Khonsari, A., Fathy, M., M. Ould-Khaoua   +11 more
core   +1 more source

Fault-tolerant control for nonlinear singular systems with time-varying delay based on fault diagnosis observer

Journal of Hebei University of Science and Technology, 2017
In order to solve the security and reliability problems of the system control in the control theory, considering that time-varying delay is widespread in many systems, thinking about solving problems by fault diagnosis and fault-tolerant control, and ...
Qiaoqiao FAN, Xuetao SHI, Lianqing SU
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Design and assessment of a multiple sensor fault tolerant robust control system [PDF]

, 2008
This paper presents an enhanced robust control design structure to realise fault tolerance towards sensor faults suitable for multi-input-multi-output (MIMO) systems implementation.
Chen, J, Yang, S.S., Chen, J., J. Chen, S.S. Yang, Yang, SS   +5 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

A new fault tolerant control scheme for non‐linear systems by T‐S fuzzy model approach

IET Control Theory & Applications, 2021
This paper is concerned with the problem of fault tolerant control for non‐linear systems with sensor faults based on the T‐S fuzzy model approach. First, a fault estimation (FE) observer with L∞ technique is designed to estimate the fault.
Yue Wu, Yang Wang, Tieshan Li, Zhixin Yang   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Review of Fault-Tolerant Control Methods for Suspension Systems: From Road Vehicles to Maglev Trains

Mathematics
Road vehicles and maglev trains have garnered significant attention, with their suspension systems being crucial for safe and stable performance. However, these systems can be compromised by faults such as sensor and actuator failures, posing risks to ...
Fei Ni, Yifan Luo, Junqi Xu, Dachuan Liu, Yougang Sun, Wen Ji   +5 more
doaj   +1 more source