Results 71 to 80 of about 99,648 (313)

Fault Diagnosis of Rotating Machinery Based on Wavelet Domain Denoising and Metric Distance

IEEE Access, 2019
In the monitoring process of petrochemical equipment rotating machinery, the collected large data easily lead to valuable data loss in the pre-processing process and affecting the accuracy of the fault diagnosis.
Naiquan Su, Xiao Li, Qianghua Zhang
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Task Data Offloading and Resource Allocation in Fog Computing With Multi-Task Delay Guarantee

IEEE Access, 2019
With the emergence of delay-sensitive task completion, computational offloading becomes increasingly desirable due to the end-user's limitations in performing computation-intense applications. Interestingly, fog computing enables computational offloading
Mithun Mukherjee, Suman Kumar, Qi Zhang, Rakesh Matam, Constandinos X. Mavromoustakis, Yunrong Lv, George Mastorakis   +6 more
doaj   +1 more source

Fault Diagnosis for a Class of Robotic Systems with Application to 2-DOF Helicopter [PDF]

, 2020
Luis Alejandro Ramírez, Manuel Alejandro Zuñiga, Gerardo Romero, E. Alcorta-García, Aldo Jonathan Muñoz‐Vázquez   +4 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Wind Speed Interval Prediction Based on Bayesian Optimized Spatio-Temporal Integration and Compression Deep Residual Network

Sensors
To address the challenge of high wind speed variability in wind farm planning, a small-sample-based spatio-temporal fusion and compression deep residual point prediction model, STiCDRS (Spatio-Temporal integration and Compression Deep Residual), is ...
Yun Wu, Yongzhen Gong, Xiaoguo Chen, Xingang Wang, Xiaoyong Li   +4 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Path-Loss-Based Fingerprint Localization Approach for Location-Based Services in Indoor Environments

IEEE Access, 2017
Wireless local area network fingerprint-based indoor localization schemes have been widely studied because of the increasing requirements of location-based services (LBSs). The features of fingerprint based localization are known to have higher precision
Jie Zhang, Guangjie Han, Ning Sun, Lei Shu   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Task Allocation Algorithm Based on Score Incentive Mechanism for Wireless Sensor Networks

International Journal of Distributed Sensor Networks, 2015
A wireless sensor network (WSN) consists of many resource constraint sensor nodes, which are always deployed in unattended environment. Therefore, the sensor nodes are vulnerable to failure and malicious attacks.
Feng Wang, Guangjie Han, Jinfang Jiang, Wei Li, Lei Shu   +4 more
doaj   +1 more source