Results 31 to 40 of about 13,286 (264)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Fault-Recovery and Repair Modeling of Discrete Event Systems Using Petri Nets

IEEE Access, 2020
Despite advances in automated manufacturing systems (AMSs), faults occur from time to time, which cannot be avoided in a complex real system. A fault is one of the primary causes of failures making some AMS operations unable to complete, and the ...
Ebrahim Ali Alzalab, Zhenhua Yu, Naiqi Wu, Husam Kaid   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Coordinated Strategy to Improve Post-Fault Characteristics of Hybrid Multi-Infeed HVDC Transmission System

Energies
The characteristics of the dynamic reactive power demand of a hybrid multi-infeed HVDC transmission system during the post-fault recovery period are analyzed and a coordinated control strategy to improve the fault recovery characteristics of the hybrid ...
Bingjie Jin, Guangjian Zhang, Zuohong Li, Shuxin Luo, Hong Dong, Chu Jin, Jindi Luo, Xinyue Zhang   +7 more
doaj   +1 more source

A Suppression Strategy for Subsequent Commutation Failures Considering Commutation Capability of Recovery Process

Shanghai Jiaotong Daxue xuebao, 2022
In order to suppress subsequent commutation failures of high voltage direct current (HVDC), the dynamic process of electrical and control quantities during system recovery is studied, and the main reason for subsequent commutation failures is proposed in
CONG Xinpeng, ZHENG Xiaodong, CAO Yaqian, TAI Nengling, MIAO Yuancheng, LI Ke
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Asynchronous Injection-Production Process: A Method to Improve Water Flooding Recovery in Complex Fault Block Reservoirs

Mathematical Problems in Engineering, 2020
The complex fault block reservoir has the characteristics of small area and many layers in vertical. Due to the influence of formation heterogeneity and well pattern, the situation that “water fingering is serious with water injection, on the contrary, driving energy is low” frequently occurs in water flooding, which makes it difficult to enhance oil ...
Shibao Yuan, Rui Wang, Haiyan Jiang, Qing Xie, Shengnan Chen, Bo Xu, Lehong Li, Yupeng Zhang   +7 more
openaire   +2 more sources

An embedded KPI-based advisory framework for monitoring and diagnosis of soft sensor degradation

Results in Engineering
Modern industrial processes rely on soft sensors to estimate process variables that are hard to measure due to expensive and sensitive hardware sensors.
Muhammad Shahid, Haslinda Zabiri, Syed Ali Ammar Taqvi   +2 more
doaj   +1 more source

Differences in perceived fairness and health outcomes in two injury compensation systems: a comparative study

BMC Public Health, 2016
Background Involvement in a compensation process following a motor vehicle collision is consistently associated with worse health status but the reasons underlying this are unclear.
Nieke A. Elbers, Alex Collie, Sheilah Hogg-Johnson, Katherine Lippel, Keri Lockwood, Ian D. Cameron   +5 more
doaj   +1 more source

DC Current Order Optimization Based Strategy for Recovery Performance Improvement of LCC-HVDC Transmission Systems

Journal of Modern Power Systems and Clean Energy, 2023
For the safe and fast recovery of line commutated converter based high-voltage direct current (LCC-HVDC) transmission systems after faults, a DC current order optimization based strategy is proposed.
Renlong Zhu, Xiaoping Zhou, Shuchen Luo, Lerong Hong, Hanhang Yin, Yifeng Liu   +5 more
doaj   +1 more source