Results 61 to 70 of about 311,379 (303)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A steady‐state analysis method for pole‐to‐pole faults under different transition resistances in voltage source converter‐based DC systems

open access: yesIET Generation, Transmission & Distribution, 2021
Fault analysis is an essential prerequisite for fault detection, location and isolation. A detailed fault analysis method on the steady state of the pole‐to‐pole fault for voltage source converter (VSC) based DC systems is presented in this paper ...
Zhengguang Xiao   +4 more
doaj   +1 more source

Assessment of a Universal Reconfiguration-less Control Approach in Open-Phase Fault Operation for Multiphase Drives [PDF]

open access: yes, 2019
Multiphase drives have been important in particular industry applications where reliability is a desired goal. The main reason for this is their inherent fault tolerance. Di erent nonlinear controllers that do not include modulation stages, like direct
Barrero, Federico   +4 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Analysis and hardware testing of cell capacitor discharge currents during DC faults in half-bridge modular multilevel converters [PDF]

open access: yes, 2015
This paper focuses on the behaviour of the cell capacitor discharge currents during DC faults in half-bridge modular multilevel converters. Active switches, not designed for fault conditions, are tripped to minimize discharge currents effect on the ...
Aboushady, A.A., Ahmed, K.H., Jovcic, D.
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Research of characteristics of transient pulse in coal mine resonant grounding system

open access: yesGong-kuang zidonghua, 2014
By means of deduction of zero-sequence current expressions when single-phase grounding fault occurs in single substation mode and multi-substation mode of coal mine resonant grounding system, polarity relationship between transient pulse of fault line ...
WANG Jinhong
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Monopolar Grounding Fault Location Method of DC Distribution Network Based on Improved ReliefF and Weighted Random Forest

open access: yesEnergies, 2022
Compared with the pole-to-pole short circuit, the fault characteristics are not obvious when a monopolar grounding fault occurs in a DC distribution network, and it is difficult to locate the fault accurately. To solve this problem, this paper proposes a
Yan Xu, Ziqi Hu, Tianxiang Ma
doaj   +1 more source

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