Results 71 to 80 of about 311,379 (303)

Temperature and pore pressure effects on the shear strength of granite in the brittle-plastic transition regime [PDF]

open access: yes, 2004
Currently published lithospheric strength profiles lack constraints from experimental data for shear failure of typical crustal materials in the brittle-plastic transition regime in wet environments.
Mochizuki, H   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

High-temperature superconducting fault current microlimiters

open access: yes, 2009
High-temperature superconducting microbridges implemented with YBa(2)Cu(3)O(7-delta) thin-films are shown to be possible fault current limiters for microelectronic devices with some elements working at temperatures below the superconducting critical ...
  +9 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

High Resistance Grounding Fault Perception and Identification Method in Asymmetric Distribution Network

open access: yesZhongguo dianli
Aiming at the problems of fault perception and identification in high resistance grounding fault of distribution network, a high resistance grounding fault perception method for parameter-asymmetric distribution network based on damping rate variation is
Penghui YANG   +5 more
doaj   +1 more source

Oscillation-Based Test Structure and Method for OTA-C Filters [PDF]

open access: yes, 2006
“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Hasan, M., Sun, Y.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Experimental Test bed to De-Risk the Navy Advanced Development Model [PDF]

open access: yes, 2017
This paper presents a reduced scale demonstration test-bed at the University of Texas’ Center for Electromechanics (UT-CEM) which is well equipped to support the development and assessment of the anticipated Navy Advanced Development Model (ADM).
Feng, X   +6 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

FBG-based fibre-optic current sensors for power systems protection : laboratory evaluation [PDF]

open access: yes, 2009
Conventional differential current unit protection schemes rely on a pair of electronic protection relays that measure current phasors separately at the boundaries of the protected zone.
Booth, Campbell   +3 more
core  

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