Results 81 to 90 of about 22,911 (308)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Operational control and protection implications of fault current limitation in distribution networks
, 2009 Rising short-circuit fault current levels is one of the problems associated with the increased presence of distributed generation (DG) in electrical networks.
Blair, S.M. +3 more
core
Process variation-aware test for resistive bridges [PDF]
, 2009 This paper analyses the behaviour of resistive bridging faults under process variation and shows that process variation has a detrimental impact on test quality in the form of test escapes.
Ingelsson, Urban +9 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Impact of fault resistance and fault distance on fault current reduction ratio of hybrid SFCL
International Transactions on Electrical Energy Systems, 2017 Summary Superconducting fault current limiters (SFCLs), as the novel power system devices, have attracted attentions in the last years. However, in order to achieve the maximum benefit from SFCLs, their interaction with power system should be comprehensively evaluated before equipping the power system with them.
Mohammad Reza Barzegar-Bafrooei +1 more
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
This paper proposes a novel method for locating single-phase grounding faults in generator stator windings with high resistance, which are typically challenging to locate due to weak fault characteristics.
Binghui Lei +7 more
core +1 more source
Simulation results of different transitional resistance fault test sets.
, 2023 Simulation results of different transitional resistance fault test sets.
Yawen Zhong (2342206) +4 more
core +1 more source
Measurement Science Review, 2012 For non-solidly earthed network, the fault localization of single phase grounding fault has been a problem. A novel fault localization and fault type recognition method of single phase grounding fault based on approximate entropy is presented.
Pang Qingle +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source