Results 171 to 180 of about 73,517 (263)

Circulating Profiles of the Bile Acid Metabolomics in Patients With Polycystic Ovary Syndrome Treated With Metformin or Canagliflozin

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.
ABSTRACT Objective Bile acids are indispensable modulators in the development of polycystic ovary syndrome (PCOS). Our previous study identified that metformin and canagliflozin have similar efficacy in patients with PCOS combined with insulin resistance (IR).
Qi Yan   +8 more
wiley   +1 more source

妊娠期糖尿病孕妇空腹血糖与妊娠结局相关性分析

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 探讨妊娠期糖尿病(GDM)空腹血糖(FBG)的特点和对妊娠结局的影响?【方法】 采用回顾性研究的方法,选择 2006年1月至2007年6月在我院进行常规产前检查和住院分娩确诊为GDM的孕妇182例,根据75 g糖耐量试验(OGTT)中FBG或FBG分为FBG正常组(A组)114例和FBG升高组(B组)68例进行临床资料分析?
doaj  

Algorithm‐Based Common Microcirculatory Framework for Monitoring and Visualizing the Integrated Pancreatic Microcirculation in Type 2 Diabetes Mellitus Mice

open access: yesJournal of Diabetes, Volume 18, Issue 2, February 2026.
Integrated monitoring of the pancreatic microcirculation utilizes a multimodal probe to simultaneously acquire microhemodynamic and oxygenation data through combined laser Doppler flowmetry and diffuse reflectance spectroscopy (DRS). Raw signals undergo algorithmic processing to extract speed‐resolved blood perfusion (BP) parameters, categorized into ...
Yuan Li   +10 more
wiley   +1 more source

Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta‐Analysis

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy   +10 more
wiley   +1 more source

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry   +2 more
wiley   +1 more source

Efficacy and safety of bi‐weekly cofrogliptin treatment replacing daily dipeptidyl peptidase‐4 inhibitors in Chinese patients with type 2 diabetes mellitus: A multicenter, open‐label, randomized controlled phase 2 trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1191-1200, February 2026.
Abstract Aim This study aimed to investigate the efficacy and safety of bi‐weekly cofrogliptin treatment as a replacement for daily dipeptidyl peptidase‐4 inhibitors (DPP‐4is) in Chinese patients with type 2 diabetes mellitus (T2DM). Methods This multicenter, open‐label, randomized controlled study assigned participants in a 1:1 ratio to either the ...
Congqing Pan   +10 more
wiley   +1 more source

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