Results 111 to 120 of about 24,384 (198)
Association between FCγ RIIA polymorphism and brucellosis [PDF]
Journal of Mazandaran University of Medical Sciences, 2007 Background and purpose: Brucellosis is a major bacterial zoonosis of global importance. Effective host defence against brucella depends on immunoglobulin G-mediated phagocytosis of the bacteria and it has been shown that the FC RIIA polymorphism (FCγ ...
M. Asmar +7 more
doaj
Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein
Chemistry–Methods, Volume 6, Issue 5, May 2026.The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley +4 more
wiley +1 more source
mAbsRozanolixizumab is a humanized anti-neonatal Fc receptor (FcRn) monoclonal antibody (mAb) of the immunoglobulin G4 (IgG4) sub-class, currently in clinical development for the treatment of IgG autoantibody-driven diseases.
Omar S. Qureshi +12 more
doaj +1 more source
European Journal of Immunology, Volume 56, Issue 5, May 2026.IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė +3 more
wiley +1 more source
Relevance of Antibody-Dependent Enhancement in COVID-19
ImmunoAntibody-dependent enhancement (ADE) is a well-established mechanism of pathology in several viral diseases, but its relevance in COVID-19 is not yet recognized.
Daniel Rodriguez-Pinto +1 more
doaj +1 more source
PLoS ONE, 2017 The causative agent of tuberculosis, Mycobacterium tuberculosis (M. tuberculosis), contains an abundant cell wall glycolipid and a crucial virulence factor, trehalose-6,6'-dimycolate (TDM).
Emmanuel C Patin +8 more
doaj +1 more source
Targeting the tumor microenvironment in colorectal peritoneal metastases
, 2020 Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim +4 more
core +1 more source
LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease
Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
Pengaruh Pemberian Klorofilin Berbagai Dosis Terhadap Indeks Fagositosis Makrofag Dan Kadar Nitric Oxide Mencit BALB/c Yang Diinfeksi Dengan Salmonella Typhimurium [PDF]
, 2014 Background: Immune responses to eliminate Salmonella infection are by activating macrophage and by producing NO. Chlorophyllin is a chlorophyll derivate that has immunomodulator properties.
Arum, P. (Puspito) +2 more
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