Results 11 to 20 of about 153,756 (258)

Evolutionary analyses of polymeric immunoglobulin receptor (pIgR) in the mammals reveals an outstanding mutation rate in the lagomorphs

Frontiers in Immunology, 2022
BackgroundThe transcytosis of polymeric immunoglobulins, IgA and IgM, across the epithelial barrier to the luminal side of mucosal tissues is mediated by the polymeric immunoglobulin receptor (pIgR).
Fabiana Neves, Fabiana Neves, Patrícia de Sousa-Pereira, Patrícia de Sousa-Pereira, Patrícia de Sousa-Pereira, José Melo-Ferreira, José Melo-Ferreira, José Melo-Ferreira, Pedro J. Esteves, Pedro J. Esteves, Pedro J. Esteves, Pedro J. Esteves, Ana Pinheiro, Ana Pinheiro   +13 more
doaj   +1 more source

Human mast cell activation through Fc receptors and Toll-like receptors

Allergology International, 2004
Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE.
Yoshimichi Okayama, Shigeru Okumura, Hisashi Tomita, Hiroko Katayama, Keisuke Yuki, Shinji Kagaya, Jun-ichi Kashiwakura, Hirohisa Saito   +7 more
doaj   +1 more source

Pentraxins and Fc Receptor-Mediated Immune Responses

Frontiers in Immunology, 2018
C-reactive protein (CRP) is a member of the pentraxin family of proteins. These proteins are highly conserved over the course of evolution being present as far back as 250 million years ago.
Jinghua Lu, Carolyn Mold, Carolyn Mold, Terry W. Du Clos, Peter D. Sun   +4 more
doaj   +1 more source

Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands.

PLoS ONE, 2020
Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions.
Sofie Mossner, Hoang T Phan, Saskia Triller, Jens M Moll, Udo Conrad, Jürgen Scheller   +5 more
doaj   +1 more source

IgA Fc Receptors

Annual Review of Immunology, 2003
The IgA receptor family comprises a number of surface receptors including the polymeric Ig receptor involved in epithelial transport of IgA/IgM, the myeloid specific IgA Fc receptor (FcαRI or CD89), the Fcα/μR, and at least two alternative IgA receptors.
Monteiro, R.C., van de Winkel, J.G.J.
openaire   +3 more sources

Fc Receptors

, 2008
The aggregation of cell surface Fc receptors by immune complexes induces a number of important antibody-dependent effector functions. It is becoming increasingly evident that the organization of key immune proteins has a significant impact on the function of these proteins.
Maree S, Powell, P Mark, Hogarth
  +6 more sources

A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptors

Scientific Reports, 2022
Fc engineering efforts are increasingly being employed to modulate interaction of antibodies with variety of Fc receptors in an effort to improve the efficacy and safety of the therapeutic antibodies.
Nidhi Nath, Becky Godat, Rod Flemming, Marjeta Urh   +3 more
doaj   +1 more source

Immunoglobulin G1 binding with various molecular receptors: A new paradigm of IgG1 as a potential adjuvant

Journal of Acute Disease, 2019
Objective: To explore the possible IgG1 binding receptors by protein-protein docking experiments. Methods: The protein-protein cognate interactions such as IgG with Fc Receptors (FcRs) potentiate signaling cascades to ameliorate antigen uptake ...
Shweta Saxena, Vignesh Sounderrajan, Saravanan Konda Mani, Shakila Harshavardhan   +3 more
doaj   +1 more source

Enhanced metabolism of LDL aggregates mediated by specific human monocyte IgG Fc receptors.

Journal of Lipid Research, 1995
Macrophage-derived foam cells are important constituents of atheromatous lesions. In addition to the scavenger receptor pathway, uptake of immune complexed lipoproteins through IgG Fc receptors (Fc gamma receptors) represents an additional pathway of ...
P M Morganelli, R A Rogers, T J Kitzmiller, A Bergeron   +3 more
doaj   +1 more source

Effect of IgG dimer concentration on the binding ability of IgG Fc fragment in IVIG to THP-1 cell surface receptors

Zhongguo shuxue zazhi, 2023
Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors.
Tingting LEI, Wei ZHANG, Changqing LI, Shengliang YE, Xi DU, Li MA   +5 more
doaj   +1 more source