Fc-conjugated C-type lectin receptors: Tools for understanding host-pathogen interactions [PDF]
, 2021 The use of soluble fusion proteins of pattern recognition receptors (PRRs) used in the detection of exogenous and endogenous ligands has helped resolve the roles of PRRs in the innate immune response to pathogens, how they shape the adaptive immune ...
JA Willment (21924464)
core +6 more sources
Characterisation of bovine leukocyte Ig-like receptors [PDF]
, 2012 Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC +8 more
core +4 more sources
NEW ROLES FOR FC RECEPTORS IN NEURODEGENERATION-THE IMPACT ON IMMUNOTHERAPY FOR ALZHEIMER’S DISEASE [PDF]
, 2014 There are an estimated 18 million Alzheimer’s disease (AD) sufferers worldwide and with no disease modifying treatment currently available, development of new therapies represents an enormous unmet clinical need.
Teeling, Jessica L. +5 more
core +1 more source
The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
, 2007 Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Periasamy Selvaraj +2 more
core +1 more source
Identification and expression of a murine cytomegalovirus early gene coding for an Fc receptor [PDF]
, 1994 Several herpesviruses, including cytomegalovirus, induce receptors for the Fc domain of murine immunoglobulin G (IgG) molecules. Viral genes coding for these receptors have been characterized only for alphaherpesviruses. In this report, we describe a new
Eggers, Maren +4 more
core +1 more source
Recombinant histidine-tagged Fc receptors.
, 2021 Recombinant histidine-tagged Fc receptors.
Stephen Anderson (2716942) +7 more
core +1 more source
Studies of Fc receptors mediating IgG transport
, 1985 Suckling rats passively acquire immunity by receptor-mediated uptake of maternal immunoglobulin G (IgG) from colostrum and milk. Receptors for the Fc region of IgG mediate its internalisation at the brush borders of endothelial cells of the proximal ...
Simister, Neil E.
core +1 more source
Adjuvant-free immunization with hemagglutinin-Fc fusion proteins as an approach to influenza vaccines [PDF]
, 2011 The hemagglutinins (HAs) of human H1 and H3 influenza viruses and avian H5 influenza virus were produced as recombinant fusion proteins with the human immunoglobulin Fc domain.
Temperton, Nigel J. +24 more
core +1 more source
Fc? receptors and autoimmunity [PDF]
, 2020 Los receptores Fc, miembros de la superfamilia de las inmunoglobulinas, participan en fenómenos inflamatorios como anti-inflamatorios, influyendo sobre la inmunidad innata y adquirida. Factores ambientales y genéticos afectan su expresión. Los receptores
CAñas, Carlos +2 more
core +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source