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Behavioral Neuroscience, 2000
Fear-potentiated startle was assessed in mice with a targeted disruption of the alpha and delta isoforms of the transcription factor cAMP response element binding protein (CREB) 24 hr after 5 tone + shock training trials. Whereas wild-type mice showed fear-potentiated startle that persisted up to 45 days after training, CREBalphadelta-/- mice failed to
W A, Falls +5 more
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Fear-potentiated startle was assessed in mice with a targeted disruption of the alpha and delta isoforms of the transcription factor cAMP response element binding protein (CREB) 24 hr after 5 tone + shock training trials. Whereas wild-type mice showed fear-potentiated startle that persisted up to 45 days after training, CREBalphadelta-/- mice failed to
W A, Falls +5 more
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Contextual fear-potentiated startle conditioning in humans: Replication and extension
Psychophysiology, 2001Contextual fear conditioning was examined using the startle reflex in two groups of participants over two sessions separated by 1/2 h. The conditioned stimulus (CS) was paired (paired group) or not (unpaired group) with an unpleasant shock during conditioning.
R, Ameli, C, Ip, C, Grillon
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Fear-potentiated startle responses in temperamentally different human infants
Developmental Psychobiology, 1998Previous research has indicated that 4-month-old human infants who exhibit high degrees of motor activity and negative affect in response to the presentation of unfamiliar auditory and visual stimuli are likely to display behavioral inhibition as toddlers, while 4-month-old infants who display high degrees of motor activity and positive affect in ...
L A, Schmidt, N A, Fox
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Shock Sensitization and Fear Potentiation of Auditory Startle Response in Hamsters
Perceptual and Motor Skills, 2007It is well known that an auditory startle response can be modulated by several processes. In the present study shock sensitization and fear potentiation were examined in 17 hamsters to assess whether response enhancement is similar for another rodent.
Hitoshi, Sasaki, Atsushi, Hanamoto
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Safety signals and human anxiety: A fear‐potentiated startle study
Anxiety, 1994AbstractThe effect of a safety signal on the magnitude of anticipatory anxiety was investigated using the fear‐potentiated startle reflex paradigm in humans. The amplitude of the acoustic startle reflex was measured during the anticipation of unpleasant electric chocks (“threat”) and during “safe” conditions. Threat and safe conditions were signaled by
C, Grillon +3 more
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Fear-potentiated startle response is remarkably similar in two laboratories
Psychopharmacology, 1996The fear-potentiated startle response paradigm is used to investigate anxiolytic properties of drugs. The first objective of the present study was to further investigate the predictive validity of this paradigm. The anxiolytics chlordiazepoxide (2.5-10 mg/ kg IP) and oxazepam (1-10 mg/kg PO) and the putative anxiolytic flesinoxan (1-10 mg/kg PO ...
Joordens, R.J.E. +3 more
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Latent inhibition of fear potentiated startle in rats.
Behavioural pharmacology, 1999Non-reinforced pre-exposure to a prospective conditioned stimulus impairs subsequent conditioning. This phenomenon is termed latent inhibition. In this report, we demonstrate latent inhibition in a classical conditioning procedure, the fear-potentiated startle reflex.
C, Schauz, M, Koch
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A further investigation of the developmental emergence of fear-potentiated startle in rats
Developmental Psychobiology, 1999This series of experiments was designed to reexamine the ontogenetic emergence of the fear-potentiated startle response in rats. Previous results (Hunt, Richardson, & Campbell, 1994) indicated that potentiated startle to a light conditioned stimulus (CS) paired with an acoustic unconditioned stimulus (US) was not observed until 30 days of age.
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Fear-Potentiated Startle Response in Mice
Pharmacology Biochemistry and Behavior, 2000James A. Mccaughran +2 more
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