Results 111 to 120 of about 1,866,866 (289)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Level of Psychological Security among Syrian Refugee Students in Ajloun Governorate Schools from their Viewpoint

المجلة الأردنية للعلوم التطبيقية-العلوم الانسانية, 2022
Ahmad Rathwan, Husni Salem, Loai Al-Issa, Reham Al-Refae   +3 more
doaj   +1 more source

Patient experiences of the Long COVID–Optimal Health Programme: a qualitative interview study in community settings

BJGP Open
Background: Long COVID (LC) symptoms persist 12 weeks or more beyond the acute infection. To date, no standardised diagnostic or treatment pathways exist. However, a holistic approach has been recommended.
Hiyam Al-Jabr, Karen Windle, Andrew Clifton, David R Thompson, David J Castle, Chantal F Ski   +5 more
doaj   +1 more source

Pilot and feasibility studies: extending the conceptual framework. [PDF]

Pilot Feasibility Stud, 2023
Bond C, Lancaster GA, Campbell M, Chan C, Eddy S, Hopewell S, Mellor K, Thabane L, Eldridge S.   +8 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Assessment of lightweight mobile nuclear power systems [PDF]

A review was made of lightweight mobile nuclear power systems (LMNPS). Data cover technical feasibility studies of LMNPS and airborne vehicles, mission studies, and non-technical conditions that are required to develop and use ...
Anderson, J. L., Rom, F. E.
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

How do pilot and feasibility studies inform randomised placebo-controlled trials in surgery? A systematic review. [PDF]

BMJ Open, 2023
Cousins S, Gormley A, Chalmers K, Campbell MK, Beard DJ, Blencowe NS, Blazeby JM.   +6 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Erratum to: BMC Palliative Care, Vol. 17

BMC Palliative Care, 2017
Pilot and Feasibility Studies
doaj   +1 more source