Results 61 to 70 of about 30,089,024 (164)

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Pancreatic function in children with non-alcoholic fatty pancreas disease

Zaporožskij Medicinskij Žurnal, 2019
Objective. To study the features of pancreatic function in children with pancreatic steatosis. Materials and methods. We examined 77 children; the average age of patients was (11.59 ± 2.82) years.
Yu. M. Stepanov, O. Yu. Lukianenko, N. Yu. Zavhorodnia, O. M. Tatarchuk, N. H. Hravirovska, I. A. Klenina   +5 more
doaj   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid, Maria Maqsood, Nimrah Ashraf, Farzeen Asghar, Nauman Khalid   +4 more
wiley   +1 more source

Animal modeling of chronic pancreatitis-induced osteoporosis with L-arginine and its preliminary mechanism [PDF]

Jichu yixue yu linchuang
Objective To establish an animal model of chronic pancreatitis-induced osteoporosis and to investigate the effects of chronic pancreatitis (CP) on bone loss in mice and the underlying mechanism. Methods Forty Kunming (KM) mice aged 6-8 weeks were divided
LI Na, MA Likai, ZHANG Junlei, DING Ning, YANG Dongli, SONG Jinyi
doaj   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Fecal calprotectin and elastase 1 determinations in patients with pancreatic diseases: a possible link between pancreatic insufficiency and intestinal inflammation

, 2007
Background: Fecal calprotectin determination has been demonstrated to be useful in diagnosing various inflammatory diseases of the gastrointestinal tract; however, data available for patients with pancreatic diseases are scarce.
Antonio M. Morselli-Labate, Lorenzo Fantini, Gianvico Melzi d'Eril, A. Morselli Labate, A. Barassi, G. V. Melzi d'Eril., G. V. Melzi d'Eril, Sergio Finazzi, Roberto Corinaldesi, G. V. Melzi d’Eril, Davide Campana, Riccardo Casadei, L. Fantini, P. Tomassetti, G. Melzi D'Eril, A. M. Morselli Labate, Alessandra Barassi, Raffaele Pezzilli, R. Corinaldesi, S. Finazzi, D. Campana, Paola Tomassetti, R. Pezzilli, F. Pateri, R. Casadei   +24 more
core   +1 more source

Exocrine dysfunction correlates with endocrinal impairment of pancreas in Type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2018
Background: Diabetes mellitus (DM) is a chronic abnormal metabolic condition, which manifests elevated blood sugar level over a prolonged period. The pancreatic endocrine system generally gets affected during diabetes, but often abnormal exocrine ...
H R Prasanna Kumar, H Basavana Gowdappa, Tejashwi Hosmani, Tejashri Urs   +3 more
doaj   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 241-259, September 2026.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Fecal and Salivary Cortisol Concentrations in Woolly (Lagothrix ssp.) and Spider Monkeys (Ateles spp.) [PDF]

, 2009
Detrimental physiological effects due to stressors can contribute to the low captive success of primates. The objective of this research was to investigate the potential impact of diet composition on cortisol concentrations in feces and saliva in woolly (
Heugten, E., van, Scott Whisnant, van Heugten, E., Whisnant, S., Swarts, H.J.M., Kimberly D. Ange-van Heugten, Ange-van Heugten, K.D., Peter Ferket, Saskia Timmer, Abahor Elias, Timmer, S., Bosch, G., Verstegen, M.W.A., Martin W. A. Verstegen, Guido Bosch, Elias, A., Hans J. M. Swarts, Eric van Heugten, Ferket, P.   +18 more
core   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 269-282, September 2026.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source