Results 101 to 110 of about 65,676 (304)

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

open access: yesAdvanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo   +5 more
wiley   +1 more source

Implications of holdfast availability and patchiness on juvenile seahorse (Hippocampus reidi) condition and welfare: Simulations in captivity

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 552-561, December 2022., 2022
Abstract Seahorses (Genus Hippocampus; Family Syngnathidae) are iconic fish characterised by tails with prehensile capabilities, which develop after the transition from planktonic to benthonic lifestyle. As a result, seahorses remain attached to vegetal structures or other elements most of the time, both in the wild and under rearing conditions. In the
Miquel Planas
wiley   +1 more source

Actionable Forecasting as a Determinant of Biological Adaptation

open access: yesAdvanced Science, EarlyView.
A new framework reveals how biological systems can achieve precise adaptation by tracking an actionable target that combines the current optimal state with its rate of change. This approach, implemented through dynamics‐informed neural networks, demonstrates that predictive mechanisms like circadian rhythms become beneficial when environmental sensing ...
Jose M. G. Vilar, Leonor Saiz
wiley   +1 more source

Do smaller chicken farms use more antibiotics? Evidence of antibiotic diffusion from Nigeria

open access: yesAgribusiness, Volume 39, Issue 1, Page 242-262, Winter 2023., 2023
Abstract Farmers across the world have been using antibiotics in poultry production for both therapeutic and nontherapeutic purposes since the mid 1900s. The literature on antibiotic diffusion and intensification is largely focused on developed countries in North America and Western Europe.
Charuta M. Parkhi   +2 more
wiley   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

Performance of limestone‐based sorbent for sorption‐enhanced gasification in dual interconnected fluidized bed reactors

open access: yesAIChE Journal, Volume 69, Issue 1, January 2023., 2023
Abstract A possibility to carry out sorption‐enhanced gasification (SEG) is represented by its integration with the calcium looping concept in dual interconnected fluidized beds (DIFB). This article is focused on the sorbent CO2 uptake performance and attrition/fragmentation tendency when operating conditions simulating those of a DIFB‐SEG process are ...
Antonio Coppola   +4 more
wiley   +1 more source

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