Results 111 to 120 of about 65,676 (304)
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source
AIChE Journal, Volume 69, Issue 1, January 2023., 2023 Abstract Lignin‐rich stream from lignocellulosic ethanol production was converted into biocrude by continuous hydrothermal liquefaction (HTL) while hydrogen was produced by aqueous phase reforming (APR) of the HTL aqueous by‐product. The effects of Na2CO3 and NaOH were investigated both in terms of processability of the feedstock as well as yield and ...
Arturo Di Fraia +8 more
wiley +1 more source
Adapted feeding strategies in fed-batch fermentation improve sugar delivery and ethanol productivity. [PDF]
Bioengineered, 2023 Hung YR +3 more
europepmc +1 more source
Determination of the maximum specific uptake capacities for glucose and oxygen in glucose‐limited fed‐batch cultivations of Escherichia coli [PDF]
, 2001 Hongying Lin +4 more
openalex +1 more source
A Model of Epigenetic Inheritance Accounts for Unexpected Adaptation to Unforeseen Challenges
Advanced Science, EarlyView.A general model of inheriting changes that are acquired during the lifetime of individuals demonstrates tremendous benefits to the population, including escape from extinction in changing environments. Contrasting the model with experimental data shows that inheritance of acquired changes enables rapid adaptation to unforeseen challenges, and accounts ...
Dino Osmanović +2 more
wiley +1 more source
AIChE Journal, Volume 69, Issue 2, February 2023., 2023 Abstract This work develops a model predictive control (MPC) scheme using online learning of recurrent neural network (RNN) models for nonlinear systems switched between multiple operating regions following a prescribed switching schedule. Specifically, an RNN model is initially developed offline to model process dynamics using the historical ...
Cheng Hu, Yuan Cao, Zhe Wu
wiley +1 more source
SIMULATION INVESTIGATIONS TOWARDS THE DEVELOPMENT OF A BACTERIAL BIOPESTICIDE FED-BATCH REACTOR
, 1998 César Cunha +2 more
openalex +1 more source
Advanced Science, EarlyView.The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He +6 more
wiley +1 more source
Flowsheet generation through hierarchical reinforcement learning and graph neural networks
AIChE Journal, Volume 69, Issue 1, January 2023., 2023 Abstract Process synthesis experiences a disruptive transformation accelerated by artificial intelligence. We propose a reinforcement learning algorithm for chemical process design based on a state‐of‐the‐art actor‐critic logic. Our proposed algorithm represents chemical processes as graphs and uses graph convolutional neural networks to learn from ...
Laura Stops +3 more
wiley +1 more source