Results 211 to 220 of about 74,171 (258)
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Fed-batch cultivation of Wautersia eutropha
Bioresource Technology, 2008Batch kinetics of polyhydroxybutyrate (PHB) synthesis in a bioreactor under controlled conditions of pH and dissolved oxygen gave a biomass of 14 g l(-1) with a PHB concentration of 6.1 g l(-1) in 60 h. The data of the batch kinetics was used to develop a mathematical model, which was then extrapolated to fed-batch by incorporating the dilution due to ...
Pallavi, Patwardhan, Ashok K, Srivastava
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2013
Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal ...
Henry C. Lim, Hwa Sung Shin
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Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal ...
Henry C. Lim, Hwa Sung Shin
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Supervision of fed-batch fermentations
Chemical Engineering Journal, 1999Process faults may be detected on-line using existing measurements based upon modelling that is entirely data driven. A multivariate statistical model is developed and used for fault diagnosis of an industrial fed-batch fermentation process. Data from several (25) batches are used to develop a model for cultivation behaviour.
Lars Gregersen, Sten Bay Jørgensen
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The Snowball Effect in Fed-Batch Bioreactions
Biotechnology Progress, 2003The bioreactor will play an important role in future biological manufacturing. For economic profit, important profiles of the feed rate in fed-batch cultures have been discussed. Unfortunately, the optimal feed rate is less robust. In these studies there exists the snowball effect in a substrate-inhibited bioprocess, in which substrate is accumulated ...
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An analysis of extended and exponentially‐fed‐batch cultures
Biotechnology and Bioengineering, 1977AbstractUnder certain conditions it is shown that an extended culture is equivalent to an exponentially‐fed‐batch culture, that an exponentially‐fed‐batch culture (and an extended culture) can be maintained at a steady state and that an exponentially‐fed‐batch culture may be mimicked by a continuous‐flow culture with a constant dilution rate ...
H C, Lim, B J, Chen, C C, Creagan
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Biological sulphide oxidation in a fed‐batch reactor
Biotechnology and Bioengineering, 1995AbstractThis study shows that, in a sulphide‐oxidizing bioreactor with a mixed culture of Thiobacilli, the formation of sulphur and sulphate as end‐products from the oxidation of sulphide can be controiledinstantaneously and reversibiy by the amount of oxygen supplied. It was found that at sulphide loading rates of up to 2.33 mmol7/L · h, both products
Janssen, A.J.H. +5 more
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Zero dynamics of continuous and FED-batch bioreactors
2003 European Control Conference (ECC), 2003The zero dynamics of simple continuous and fed-batch biore-actors is investigated in this paper for different input and output selections. A function λ generating the necessary coordinates transformation has been determined analytically for each case solving a simple PDE, and the resulting coordinates transformations have found to be invertible on the ...
Gábor Szederkényi +2 more
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An adaptive control algorithm for fed‐batch culture
Biotechnology and Bioengineering, 1984AbstractThe implementation of adaptive control for a fed‐batch culture in order to maximize the output of product based on a self‐adjusting model is discussed in the present work. Optimization methods were applied to the generalized mathematical model of a fed‐batch fermentation process to determine control algorithms that could be used for on‐line ...
J, Stanissis, D, Levisauskas
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The control of fed-batch fermentation processes—A survey
Automatica, 1987A survey of the control of fermentation processes operated in fed-batch mode is presented. Truely optimal conditions can only be found by minimizing (or maximizing) a cost criterion subject ot the constraints imposed by a mathematical model of the process.
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Reachability of nonlinear fed‐batch fermentation processes
International Journal of Robust and Nonlinear Control, 2002AbstractThe reachability of a simple nonlinear fed‐batch fermentation process model is investigated in this paper. It is shown that the known difficulties of controlling such processes are primarily caused by the fact that the rank of the reachability distribution is always less than the number of state variables.Furthermore, a co‐ordinates ...
Szederkényi, G. +2 more
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