Results 31 to 40 of about 65,676 (304)

Optimization of process parameters and fermentation strategy for xylanase production in a stirred tank reactor using a mutant Aspergillus nidulans strain

Biotechnology Reports, 2020
The present work studied the optimization of aeration rate, agitation rate and oxygen transfer and the use of various batch fermentation strategies for xylanase production from a recombinant Aspergillus nidulans strain in a 3 L stirred tank reactor ...
Asmaa Abdella, Fernando Segato, Mark R. Wilkins   +2 more
doaj  

Continuous Production of Biogenic Magnetite Nanoparticles by the Marine Bacterium Magnetovibrio blakemorei Strain MV-1^T with a Nitrous Oxide Injection Strategy

Marine Drugs, 2022
Magnetotactic bacteria (MTB) produce magnetosomes, which are membrane-embedded magnetic nanoparticles. Despite their technological applicability, the production of magnetite magnetosomes depends on the cultivation of MTB, which results in low yields ...
Tarcisio Correa, Mateus G. Godoy, Dennis A. Bazylinski, Fernanda Abreu   +3 more
doaj   +1 more source

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

FEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda, Hiroshi Iwakura, Takuya Ensho, Mika Bando‐Shimizu, Asako Doi, Norihiko Matsutani, Shuhei Morita, Hidefumi Inaba, Hiroyuki Ariyasu, Naoki Fukuda, Keiji Hayata, Toshiyasu Ojima, Masahiro Nishi, Taka‐aki Matsuoka, Hiroki Yamaue, Takashi Akamizu   +15 more
wiley   +1 more source

Optimization of Bacillus subtilis cell growth effecting jiean-peptide production in fed batch fermentation using central composite design

Electronic Journal of Biotechnology, 2014
Background: Optimization of nutrient feeding was developed to improve the growth of Bacillus subtilis in fed batch fermentation to increase the production of jiean-peptide (JAA).
Juan Zhong, Xiaoyong Zhang, Yanli Ren, Jie Yang, Hong Tan, Jinyan Zhou   +5 more
doaj   +1 more source

Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodinium cohnii

Microbial Cell Factories, 2020
Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity.
Liangsen Liu, Fangzhong Wang, Guangsheng Pei, Jinyu Cui, Jinjin Diao, Mingming Lv, Lei Chen, Weiwen Zhang   +7 more
doaj   +1 more source

Model Predictive Control—A Stand Out among Competitors for Fed-Batch Fermentation Improvement

Fermentation, 2023
The fed-batch cultivation is in many ways a benchmark for fermentation processes, and it has been an attractive choice for the biotechnological production of various products in the past decades.
Emils Bolmanis, Konstantins Dubencovs, Arturs Suleiko, Juris Vanags   +3 more
doaj   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Cell factory for γ-aminobutyric acid (GABA) production using Bifidobacterium adolescentis

Microbial Cell Factories, 2022
Background Bifidobacteria are gram-positive, probiotic, and generally regarded as safe bacteria. Techniques such as transformation, gene knockout, and heterologous gene expression have been established for Bifidobacterium, indicating that this bacterium ...
Hend Altaib, Tomoya Kozakai, Yassien Badr, Hazuki Nakao, Mahmoud A. M. El-Nouby, Emiko Yanase, Izumi Nomura, Tohru Suzuki   +7 more
doaj   +1 more source

One Approach for Dynamic L-lysine Modelling of Repeated Fed-batch Fermentation [PDF]

Bioautomation, 2007
This article deals with establishment of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-lysine production.
Kalin Todorov, Ignat Dimov, Tzanko Georgiev, Velichka Ivanova, Juliy Kristeva, Alexander Ratkov   +5 more
doaj  

Closing the gap in plan quality: Leveraging deep‐learning dose prediction for adaptive radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Balancing quality and efficiency has been a challenge for online adaptive therapy. Most systems start the online re‐optimization with the original planning goals. While some systems allow planners to modify the planning goals, achieving a high‐quality plan within time constraints remains a common barrier.
Sean J. Domal, Austen Maniscalco, Justin Visak, Michael Dohopolski, Dominic Moon, Vladimir Avkshtol, Dan Nguyen, Steve Jiang, David Sher, Mu‐ Han Lin   +9 more
wiley   +1 more source