Results 241 to 250 of about 111,815 (303)

A Bioengineering Approach for Maximum Histidine Production in Fed-Batch Culture [PDF]

open access: yes
Patoomporn, Chim-Anage   +1 more
core  

Fed-batch culture technology

Biotechnology Advances, 1986
The use of fed-batch procedures offers distinct advantages over other modes of operation of bioreactors, and is a widely researched technique. These advantages are discussed; some uses of fed-batch procedures and the associated methods of modelling and control are reviewed.
B J, Minihane, D E, Brown
openaire   +4 more sources

Perchloroethylene utilization by methanogenic fed-batch cultures

Applied Biochemistry and Biotechnology, 1996
Anaerobic sludge granules from two different sources were maintained in serum bottles and fed at 3-d intervals in the presence of 0.2 ppm perchloroethylene (PCE). Following acclimation periods ranging from 48-79 d, PCE degradation was observed with 95% utilization in 3 d. Only granules amended with formate as a cosubstrate showed PCE-degrading activity,
Herve Garant, Lee R. Lynd
openaire   +2 more sources

Metabolically optimised BHK cell fed-batch cultures

Journal of Biotechnology, 2000
The aim of this work was the optimisation of a fed-batch culture by metabolic confinement of BHK21 cells producing an antibody/cytokine fusion protein with potential application in tumour-targeted therapy. Previous results showed that at very low nutrient concentrations, a metabolic shift towards more efficient metabolic pathways occurs.
H J, Cruz, J L, Moreira, M J, Carrondo
openaire   +2 more sources

An adaptive control algorithm for fed‐batch culture

Biotechnology and Bioengineering, 1984
AbstractThe implementation of adaptive control for a fed‐batch culture in order to maximize the output of product based on a self‐adjusting model is discussed in the present work. Optimization methods were applied to the generalized mathematical model of a fed‐batch fermentation process to determine control algorithms that could be used for on‐line ...
J, Stanissis, D, Levisauskas
openaire   +2 more sources

Fed-Batch Cultures

2013
Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal ...
Henry C. Lim, Hwa Sung Shin
openaire   +1 more source

Feed Optimization in Fed-Batch Culture

2013
Fed-batch processes are a current preference for the production of recombinant proteins in mammalian cells. The use of nutrient feeding prevents the depletion of important medium components and results in improved culture longevity and high cell and product yields.
Costa, A. R.   +4 more
openaire   +3 more sources

An analysis of extended and exponentially‐fed‐batch cultures

Biotechnology and Bioengineering, 1977
AbstractUnder certain conditions it is shown that an extended culture is equivalent to an exponentially‐fed‐batch culture, that an exponentially‐fed‐batch culture (and an extended culture) can be maintained at a steady state and that an exponentially‐fed‐batch culture may be mimicked by a continuous‐flow culture with a constant dilution rate ...
H C, Lim, B J, Chen, C C, Creagan
openaire   +2 more sources

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