Results 31 to 40 of about 183,147 (267)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The positive impacts of tea polyphenols on the growth performance, immune responses, and hepatic health of largemouth bass (Micropterus salmoides) under high fat diets

Aquaculture Reports
The objective of this study was to assess the impacts of tea polyphenols (TP) on the growth performance, immune responses, and hepatic health of largemouth bass (M. salmoides) under high fat diets. A total of 375 individuals (average initial weight: 34 ± 
Digen Qin, Jiale Chen, Junxiong Li, Zhiyou Liu, Weibin Huang, Hao Liu, Hengyang Song, Wenshan Cai, Beiping Tan, Xiaohui Dong   +9 more
doaj   +1 more source

Effects of Soluble and Insoluble Non-Starch Polysaccharides on Growth Performance, Digestive Enzyme Activity, Antioxidant Capacity, and Intestinal Flora of Juvenile Genetic of Improvement of Farmed Tilapia (Oreochromis niloticus)

Frontiers in Marine Science, 2022
This study aimed to evaluate the effects of soluble and insoluble non-starch polysaccharides (NSPs) on growth performance, digestive enzyme activity, antioxidant capacity, and intestinal flora of juvenile GIFT tilapia (Oreochromis niloticus).
Yu Liu, Yu Liu, Yu Liu, Junming Deng, Junming Deng, Junming Deng, Beiping Tan, Beiping Tan, Beiping Tan, Shiwei Xie, Shiwei Xie, Shiwei Xie, Wei Zhang, Wei Zhang, Wei Zhang   +14 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Ameliorative effects of lycopene on oxidized fish oil-induced growth reduction and hepatic oxidative alterations of Jinhu grouper (Epinephelus fuscoguttatus ♀ × Epinephelus tukula ♂)

Aquaculture Reports
This study investigated the effects of adding lycopene to oxidized fish oil diets on the growth and liver health in Jinhu grouper (Epinephelus fuscoguttatus ♀ × Epinephelus tukula ♂).
Guoyong Huang, Weibin Huang, Guangcai Fu, Hengyang Song, Wenshan Cai, Yubin Liu, Yuxuan Han, Yilin Yao, Beiping Tan, Xiaohui Dong   +9 more
doaj   +1 more source

Feeding juvenile largemouth bass (Micropterus salmoides) with carboxymethyl cellulose with different viscous: Impacts on nutrient digestibility, growth, and hepatic and gut morphology

Frontiers in Marine Science, 2022
A 56-day trial investigated the impact of the dietary inclusion of cellulose with different viscosities on the growth, nutrient digestibility, serum biochemical indices, and the hepatic and gut morphology of largemouth bass juveniles.
Yu Liu, Yu Liu, Yu Liu, Jiongting Fan, Jiongting Fan, Jiongting Fan, Hang Zhou, Hang Zhou, Hang Zhou, Yumeng Zhang, Yumeng Zhang, Yumeng Zhang, Huajing Huang, Huajing Huang, Huajing Huang, Yixiong Cao, Yixiong Cao, Yixiong Cao, Wei Zhang, Wei Zhang, Wei Zhang, Junming Deng, Junming Deng, Junming Deng, Beiping Tan, Beiping Tan, Beiping Tan   +26 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effects of dietary n-3HUFA levels on growth, antioxidant capacity, and ovarian development in Litopenaeus vannamei broodstock shrimp

Aquaculture Reports
The present study investigated the effects of dietary n-3 highly unsaturated fatty acids (n-3 HUFA) on the growth, antioxidant capacity, and ovarian development of female Litopenaeus vannamei broodstock. Five experimental diets with varying levels of n-3
Weibin Huang, Biao Li, Beiping Tan, Digen Qin, Zhiyue Li, Xintong Su, Yansheng Liu, Shuang Zhang, Shiwei Xie, Xiaohui Dong   +9 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source