Results 51 to 60 of about 4,106,941 (234)

The positive effects of dietary inositol on juvenile hybrid grouper (♀Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatu) fed high-lipid diets: Growth performance, intestinal digestive enzymes, tissue morphology, and intestinal microbiota

Aquaculture Reports
The aim of study was to explore the beneficial effects of adding inositol to high-lipid diets on intestinal digestive enzymes, tissue morphology, and intestinal microbiota in juvenile hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatu)
Biao Li, Simiao Pan, Weibin Huang, Menglong Zhou, Hao Liu, Baiquan Lu, Hengyang Song, Wenshan Cai, Beiping Tan, Yuanzhi Yang, Xiaohui Dong   +10 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Effect of three polychaetes on growth and reproductive performance, biochemical indices and histology of different tissues in the female Pacific white shrimp, Litopenaeus vannamei broodstock

Animal Nutrition
A 30-day feeding trial was conducted to assess the effect of three fresh-live polychaetes as diets on growth and reproductive performance, biochemical indices and histology of different tissues in female Pacific white shrimp (Litopenaeus vannamei ...
Shuaipeng Li, Hao Liu, Weibin Huang, Shipei Yang, Mingsheng Xie, Menglong Zhou, Baiquan Lu, Biao Li, Beiping Tan, Yuanzhi Yang, Xiaohui Dong   +10 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Effects of aflatoxin B1 on subacute exposure of hybrid groupers (Epinephelus fuscoguttatus♀ × Epinephelus lanceolatus♂): Growth, liver histology, and integrated liver transcriptome and metabolome analysis

Animal Nutrition
With the increasing incorporation of plant-based ingredients into the grouper diet, the issue of aflatoxin B1 (AFB1) contamination in the diet has become a significant concern. In this study, the negative effects of AFB1 on the growth and liver health of
Hao Liu, Shuqing Liang, Weibin Huang, Yuanzhi Yang, Menglong Zhou, Baiquan Lu, Biao Li, Wenshan Cai, Hengyang Song, Beiping Tan, Xiaohui Dong   +10 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Effects of dietary protein levels on lipid metabolism and intestinal health of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed high-lipid diets

Aquaculture Reports
The study aims to investigate the effects of dietary protein levels in high-lipid diets (16 %) on lipid metabolism and intestinal health of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus).
Wenshan Cai, Weibin Huang, Guangcai Fu, Hengyang Song, Hao Liu, Menglong Zhou, Biao Li, Baiquan Lu, Yansheng Liu, Beiping Tan, Xiaohui Dong   +10 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source