Results 71 to 80 of about 972,094 (301)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

EFFECT OF FEED RESTRICTION ON GROWTH PERFORMANCE, CARCASS QUALITY, SOME BLOOD PARAMETERS, DIGESTIVE AND PHYSIOLOGICAL INDICES OF MUSCOVY DUCKS [PDF]

Egyptian Poultry Science
A study was carried out to assess how feed restriction affected the growth performance, carcass characteristics, some blood parameters, digestive and physiological status of Muscovy ducks.
Enas Ahmed, A. R. Gomaa, Nada Shahawy, Esraa Helbawi   +3 more
doaj   +1 more source

Nutrigenomic analyses reveal miRNAs and mRNAs affected by feed restriction in the mammary gland of midlactation dairy cows.

PLoS ONE, 2021
The objective of this study was to investigate the effects of feed restriction on mammary miRNAs and coding gene expression in midlactation cows. Five Holstein cows and 6 Montbéliarde cows underwent 6 days of feed restriction, during which feed allowance
Pierre-Alexis Billa, Yannick Faulconnier, Tao Ye, Céline Bourdon, José A A Pires, Christine Leroux   +5 more
doaj   +1 more source

Temporal feed restriction and overstocking increase competition for feed by dairy cattle [PDF]

Journal of Dairy Science, 2011
Dairy cows are often overstocked. Some managers are now using "slick bunk" (i.e., feeding for 0% orts) management to save on feed costs, but this reduces the time that cows have access to feed. Both practices may increase competition and affect feeding behavior in dairy cows.
L K M, Collings, D M, Weary, N, Chapinal, M A G, von Keyserlingk   +3 more
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Metabolic response in blood and cerebrospinal fluid during feed restriction: Identification of potential metabolic signals associated with individual feed intake rebound

Journal of Dairy Science
: The aim of this study was to evaluate the effects of feed restriction and refeeding on metabolic and AA profiles in blood serum, and on cerebrospinal fluid (CSF) profiles during the feed restriction period, using a controlled feeding model ...
M.N. Viera, A.L. Astessiano, E. Jorge-Smeding, A.I. Trujillo   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Relationship of Restricted Feeding and Medication to Coccidiosis Control

Poultry Science, 1980
Hubbard breeder pullets were fed a complete pullet developer ration on an ad libitum (AL) or restricted feeding (RF) regimen. The ration either was unmedicated or contained .0125% amprolium, .0125% clopidol, or .0110% monensin. The relationship between the feeding schedule and coccidial infection was determined on the basis of 1) efficacy of the ...
M D, Ruff, M B, Chute
openaire   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source