Results 41 to 50 of about 2,348,564 (281)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Nonlinear Science, 2016 A new method is proposed to numerically integrate a dynamical system on a manifold such that the trajectory stably remains on the manifold and preserves first integrals of the system. The idea is that given an initial point in the manifold we extend the dynamics from the manifold to its ambient Euclidean space and then modify the dynamics outside the ...
Dong Eui Chang +2 more
openaire +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of Dr. NTR University of Health Sciences, 2022 Background: The department of biochemistry at a tertiary care teaching hospital had the first offline early clinical exposure (ECE) on gout in October 2021 in the aftermath of COVID 19.
Kolli Harika +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Two-Mode Hereditary Model of Solar Dynamo
MathematicsThe magnetic field of the Sun is formed by the mechanism of hydromagnetic dynamo. In this mechanism, the flow of the conducting medium (plasma) of the convective zone generates a magnetic field, and this field corrects the flow using the Lorentz force ...
Evgeny Kazakov +2 more
doaj +1 more source
Geri Bildirimin Araştırma Görevlilerinin Öz-Yeterlilikleri Üzerindeki Etkisi
Journal of Human and Work, 2016 Çalışma araştırma görevlilerinin akademik kariyerlerinin ilk zamanlarında yaptıkları akademik veya idari işler ve birlikte çalıştıkları diğer akademisyenlerle iletişimleri sonucu kendileriyle ilgili elde ettikleri bilgilerin kariyer gelişimindeki rolünü ...
Bilal Çankır
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Revista Ibero-Americana de Ciência da Informação, 2012 Apresenta estudo sobre a relevância adotada pelo Repositório Institucional da Universidade de Brasília e o feedback do usuário às respostas de recuperação da informação.
Carlos Duarte Oliveira Junior +3 more
doaj
Apunts: Educación Física y DeportesLas instrucciones técnicas y el feedback son las conductas más utilizadas en la actuación de los entrenadores y entrenadoras. Sin embargo, la investigación se ha centrado en el contenido pedagógico de estas, por lo que se ha descuidado la forma en que se
Lídia Ordeix +2 more
doaj +1 more source