Results 51 to 60 of about 1,222,276 (249)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Frontiers in PsychologyIntroductionPsychologists are particularly interested in how people operate in stressful settings. The sporting arena is a “natural laboratory” for studying how people behave and perform in high-pressure situations.
Chunhua Li, Yangqing Zhao
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Comunicación interna y su relación con la satisfacción laboral
AcademoEsta revisión de la literatura tiene como objetivo explorar la evolución histórica y el papel estratégico de la comunicación interna en las organizaciones, con un enfoque especial en su impacto en la satisfacción laboral. Mediante una revisión narrativa,
Christian Benitez
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Faire descendre le maître de son piédestal. Retour sur parcours d’un formateur-chercheur
Éducation et SocialisationThis paper takes a look back at my teaching career, traced through the eyes of the ignorant master, a figure proposed by Jacques Rancière in the light of the work of Joseph Jacotot.
Philippe Glâtre
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Sound and vision: evaluating the student experience of audio-visual feedback in higher education
Journal of Learning Development in Higher EducationTechnology enhanced feedback methods such as video feedback are increasingly employed with a notable shift towards embracing remote means of communication during and after the Covid-19 pandemic. Greater use of distance and electronic learning can result
Jill Gould, Patricia Day
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source