Results 51 to 60 of about 2,348,564 (281)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

MaReS (Magdeburg Reflective Writing Scoring Rubric for Feedback) – development of a feedback method for reflective writing in health professions education: A pilot study in veterinary medicine

GMS Journal for Medical Education
Aim: The aim of the study was to develop a scoring rubric that provides valuable feedback to students and to gather evidence for its construct validity.
Ramspott, Sabine, Sonntag, Ulrike, Härtl, Anja, Rüttermann, Stefan, Roller, Doris, Giesler, Marianne, Hempel, Linn   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The effects of mathematical ability and motivational beliefs on students’ perceptions of feedback usefulness

Frontiers in Education
Research has shown that students’ learning gains in mathematics are greater when they work with problems rather than routine tasks. These learning gains from problem-solving activities may be enhanced by providing feedback that does not give away the ...
Sharmin Söderström, Sharmin Söderström, Torulf Palm, Torulf Palm, Carina Granberg, Carina Granberg   +5 more
doaj   +1 more source

Targeted feedback for Indonesian-speaking classrooms in higher education context: A perspective from educators’ lens [PDF]

In today's interconnected world, excellent communication is essential to develop relationships and cooperate with people from various cultural backgrounds.
Rozanah Katrina Herda,Ihtiara Fitrianingsih,Dalwinder Kaur
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Blended Feedback: Delivery of feedback as digital audio on a computer programming unit [PDF]

, 2013
Traditionally students are taught in a classroom, lecture theatre, or laboratory, by staff. They are encouraged to question, discuss, and participate in learning activities maximizing learning potential and to engage in dialogue as a means of monitoring ...
Atfield-Cutts, S., Jeary, S.
core   +4 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effective Implementation of Entrustable Professional Activities in Medical Colleges: Faculty Perspective

Journal of the Scientific Society
Entrustable professional activities (EPAs) refer to the key activities that medical students should be in a position to perform on their own by the time of completion of their training.
Saurabh RamBihariLal Shrivastava, Shubhada Gade, Sunita Vagha   +2 more
doaj   +1 more source