Results 51 to 60 of about 282,811 (270)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Mirror Feedback Effect for Patients after Spinal Lumbar Disc Hernia Removal during the Secondary Rehabilitation Stage

open access: yesReabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2019
Background. Literature does not provide sufcient data on the efciency of mirror feedback in physiotherapy as an additional measure for effective recovery of patients after the spinal lumbar disc hernia removal surgery during the secondary rehabilitation ...
Ligita Overlingaitė   +1 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Feedback stabilization of dynamical systems with switched delays

open access: yes, 2012
We analyze a classification of two main families of controllers that are of interest when the feedback loop is subject to switching propagation delays due to routing via a wireless multi-hop communication network. We show that we can cast this problem as
D'Innocenzo, Alessandro   +2 more
core   +1 more source

Feedback stabilization initiative [PDF]

open access: yes, 1997
Much progress has been made in attaining high confinement regimes in magnetic confinement devices. These operating modes tend to be transient, however, due to the onset of MHD instabilities, and their stabilization is critical for improved performance at steady state.
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Feedback stabilization of pure states in quantum transport

open access: yes, 2011
We propose a feedback control scheme for generating and stabilizing pure states of transport devices, such as charge qubits, under non-equilibrium conditions. The purification of the device state is conditioned on single electron jumps and leaves a clear
Brandes, Tobias   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Event-Triggered Control for the Stabilization of Probabilistic Boolean Control Networks

open access: yesComplexity, 2018
This paper realizes global stabilization for probabilistic Boolean control networks (PBCNs) with event-triggered state feedback control (ETSFC). Via the semitensor product (STP) of matrices, PBCNs with ETSFC are converted into discrete-time algebraic ...
Shiyong Zhu   +4 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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