Results 91 to 100 of about 245,531 (271)

Focus on changing fire regimes: interactions with climate, ecosystems, and society

open access: yesEnvironmental Research Letters, 2020
Fire is a complex Earth system phenomenon that fundamentally affects vegetation distributions, biogeochemical cycling, climate, and human society across most of Earth’s land surface.
Brendan M Rogers   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Water Ice Cloud Feedbacks over the North Polar Residual Cap at Moderate Obliquity [PDF]

open access: yes
Several global climate modeling studies have now shown that water ice clouds can warm the surface 10s of K at moderate obliquities [1,2,3]. Significant greenhouse warming occurs because the predicted clouds are optically thick, the cloud particles are ...
Haberle, R. M., Kahre, M. A.
core   +1 more source

COMPUTER TECHNOLOGIES IN LINE STRUCTURE ROUTING

open access: yesРоссийский технологический журнал, 2017
Under study are two approaches to creating computer programs for computer-aided design of linear structures trails. The first approach, which realised in the existing CAD of linear structures, is not focused on the optimization of the design decisions ...
V. I. Struchenkov
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Coress feedback [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2012
CORESS is a confidential reporting system for surgery. The purpose of CORESS is to promote safety in surgical practice, both within the NHS and in the independent sector.
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Detection and Filtering of Collaborative Malicious Users in Reputation System using Quality Repository Approach [PDF]

open access: yes, 2013
Online reputation system is gaining popularity as it helps a user to be sure about the quality of a product/service he wants to buy. Nonetheless online reputation system is not immune from attack.
HK, Jnanamurthy, Singh, Sanjay
core  

Deforestation Could Push Amazonia Close to a Tipping Point Under Future Climate Change

open access: yesGeophysical Research Letters
We use a coupled land‐surface‐atmosphere single‐column model to examine the effects of deforestation and changed advective moisture flux (AMF) on the Amazonian system.
László Hunor Hajdu   +3 more
doaj   +1 more source

Irrigation experiments in the lab: trust, environmental variability, and collective action

open access: yesEcology and Society, 2015
Research on collective action and common-pool resources is extensive. However, little work has concentrated on the effect of variability in resource availability and collective action, especially in the context of asymmetric access to resources.
Jacopo A. Baggio   +3 more
doaj   +1 more source

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