Results 91 to 100 of about 246,352 (271)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Although the importance of providing feedback to our fellows, residents, and colleagues is acknowledged, this key step in the acquisition of clinical skills is often omitted from training programs. When effective feedback is provided and focuses on directly observable skills and behaviors, important personal and educational progress can occur.
openaire +2 more sources
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
COMPUTER TECHNOLOGIES IN LINE STRUCTURE ROUTING
Under study are two approaches to creating computer programs for computer-aided design of linear structures trails. The first approach, which realised in the existing CAD of linear structures, is not focused on the optimization of the design decisions ...
V. I. Struchenkov
doaj +1 more source
CORESS is a confidential reporting system for surgery. The purpose of CORESS is to promote safety in surgical practice, both within the NHS and in the independent sector.
openaire +2 more sources
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Deforestation Could Push Amazonia Close to a Tipping Point Under Future Climate Change
We use a coupled land‐surface‐atmosphere single‐column model to examine the effects of deforestation and changed advective moisture flux (AMF) on the Amazonian system.
László Hunor Hajdu +3 more
doaj +1 more source
Water Ice Cloud Feedbacks over the North Polar Residual Cap at Moderate Obliquity [PDF]
Several global climate modeling studies have now shown that water ice clouds can warm the surface 10s of K at moderate obliquities [1,2,3]. Significant greenhouse warming occurs because the predicted clouds are optically thick, the cloud particles are ...
Haberle, R. M., Kahre, M. A.
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

