Results 91 to 100 of about 246,352 (271)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Providing Feedback

open access: yesGastrointestinal Endoscopy Clinics of North America, 1995
Although the importance of providing feedback to our fellows, residents, and colleagues is acknowledged, this key step in the acquisition of clinical skills is often omitted from training programs. When effective feedback is provided and focuses on directly observable skills and behaviors, important personal and educational progress can occur.
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

COMPUTER TECHNOLOGIES IN LINE STRUCTURE ROUTING

open access: yesРоссийский технологический журнал, 2017
Under study are two approaches to creating computer programs for computer-aided design of linear structures trails. The first approach, which realised in the existing CAD of linear structures, is not focused on the optimization of the design decisions ...
V. I. Struchenkov
doaj   +1 more source

Coress feedback [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2012
CORESS is a confidential reporting system for surgery. The purpose of CORESS is to promote safety in surgical practice, both within the NHS and in the independent sector.
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Deforestation Could Push Amazonia Close to a Tipping Point Under Future Climate Change

open access: yesGeophysical Research Letters
We use a coupled land‐surface‐atmosphere single‐column model to examine the effects of deforestation and changed advective moisture flux (AMF) on the Amazonian system.
László Hunor Hajdu   +3 more
doaj   +1 more source

Water Ice Cloud Feedbacks over the North Polar Residual Cap at Moderate Obliquity [PDF]

open access: yes
Several global climate modeling studies have now shown that water ice clouds can warm the surface 10s of K at moderate obliquities [1,2,3]. Significant greenhouse warming occurs because the predicted clouds are optically thick, the cloud particles are ...
Haberle, R. M., Kahre, M. A.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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