Results 41 to 50 of about 275,010 (266)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Prácticas proambientales para la sostenibilidad: Impulsando un futuro más verde a través de iniciativas globales y locales

Journal of Behavior and Feeding
En un mundo impactado por el cambio climático y la degradación ambiental, la adopción de prácticas proambientales surge como una de las soluciones clave para alcanzar la sostenibilidad.
Fátima Antonia Montes Garcia, Jose Roberto Espinoza Villegas   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Efectos del consumo de proteína a base de pasto verde de trigo y meditación sobre la oxigenación en sangre en jóvenes del Centro Universitario de los Valles

Journal of Behavior and Feeding
El presente proyecto es un trabajo interdisciplinario que vincula conocimientos de la nutrición y la psicología. Específicamente, se evaluó el efecto del consumo de un suplemento alimenticio a base de pasto verde de trigo (marca Bien Verde) sobre la ...
Laura Vanesa Solano Santos, Luis Alfaro Hernández   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

La inflamación como modulador de la conducta y el comportamiento alimentario durante la enfermedad

Journal of Behavior and Feeding
La respuesta inflamatoria es un fenómeno inmunológico fundamental que se genera tras la infección o señales de daño en el organismo. En este proceso, participan activamente múltiples citocinas, moléculas que, por su pleiotropismo, no solo coordinan ...
Heysel Murillo Cazares, Zyanya Reyes Castillo, Elia Herminia Valdés Miramontes   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Perinatal programming effects on feeding behavior

Journal of Behavior and Feeding
To address the growing prevalence of obesity and its associated metabolic consequences, it is essential to understand the evolutionary origins of health and disease.
Ana Patricia Zepeda Salvador, Ana Cristina Espinoza Gallardo, Dalila Betsabee Meza Rodríguez, Yadira Vianet Martínez Vázquez, Aida Gabriela Anaya Flores, Sofía Castro Botero, Fernando Chávez Corona, Jorge Adalberto Ramos López, Berenice Sánchez Caballero, Alma Gabriela Martínez Moreno   +9 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Integración del contexto en las intervenciones nutricionales: Reflexiones y aproximaciones

Journal of Behavior and Feeding
Las intervenciones nutricionales tienen como finalidad el mejorar la salud y el bienestar de los individuos; sin embargo, ante el latente aumento de las enfermedades crónico-degenerativas y la poca eficacia de estas intervenciones, es indispensable ...
Yadira Vianet Martínez-Vázquez, Ana Cristina Espinoza-Gallardo , Aida Gabriela Anaya-Flores   +2 more
doaj   +1 more source