Results 61 to 70 of about 4,729,067 (299)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
En un mundo impactado por el cambio climático y la degradación ambiental, la adopción de prácticas proambientales surge como una de las soluciones clave para alcanzar la sostenibilidad.
Fátima Antonia Montes Garcia +1 more
doaj +1 more source
Growing evidence suggests that ocean acidification (OA) may affect animal behaviors such as feeding. Although gustation plays a crucial role in evaluating the quality and palatability of food and ultimately influences whether or not teleosts consume the ...
Tang, Y +5 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
El presente proyecto es un trabajo interdisciplinario que vincula conocimientos de la nutrición y la psicología. Específicamente, se evaluó el efecto del consumo de un suplemento alimenticio a base de pasto verde de trigo (marca Bien Verde) sobre la ...
Laura Vanesa Solano Santos +1 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
La inflamación como modulador de la conducta y el comportamiento alimentario durante la enfermedad
La respuesta inflamatoria es un fenómeno inmunológico fundamental que se genera tras la infección o señales de daño en el organismo. En este proceso, participan activamente múltiples citocinas, moléculas que, por su pleiotropismo, no solo coordinan ...
Heysel Murillo Cazares +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Perinatal programming effects on feeding behavior
To address the growing prevalence of obesity and its associated metabolic consequences, it is essential to understand the evolutionary origins of health and disease.
Ana Patricia Zepeda Salvador +9 more
doaj +1 more source

