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An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats. [PDF]

open access: yesViruses, 2022
Feline infectious peritonitis (FIP) is a fatal disease of cats that currently lacks licensed and affordable vaccines or antiviral therapeutics. The disease has a spectrum of clinical presentations including an effusive (“wet”) form and non-effusive (“dry”
Cook S   +10 more
europepmc   +2 more sources

Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites. [PDF]

open access: yesViruses, 2019
Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases.
Chen S   +8 more
europepmc   +2 more sources

Cornell Feline Health Center News, No. 4, August 1981 [PDF]

open access: yes, 1981
Topics in this issue include: Central Nervous System Disease in the Cat (Brian A. Summers); Diagnosis of Virus Infections in Cats (Richard C. Weiss); Georgraphical Distribution of Feline Infectious Peritonitis (FIP) (J. E. Barlough, J. C. Adsit, F.
Cornell Feline Health Center
core   +4 more sources

Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV). [PDF]

open access: yesBMC Vet Res, 2019
Background Feline infectious peritonitis (FIP) is considered highly fatal in its naturally occurring form, although up to 36% of cats resist disease after experimental infection, suggesting that cats in nature may also resist development of FIP in the ...
Mustaffa-Kamal F   +3 more
europepmc   +2 more sources

Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis [PDF]

open access: yes, 2014
Recent evidence suggests that a mutation in the spike protein gene of feline coronavirus (FCoV), which results in an amino acid change from methionine to leucine at position 1058, may be associated with feline infectious peritonitis (FIP).
Tasker, S   +21 more
core   +1 more source

Comparative in vivo analysis of recombinant type II feline coronaviruses with truncated and completed ORF3 region.

open access: yesPLoS ONE, 2014
Our previous in vitro comparative study on a feline coronavirus (FCoV) pair, differing only in the intactness of their ORF3abc regions, showed that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II ...
Ádám Bálint   +3 more
doaj   +1 more source

Serotype I and II Feline Coronavirus Replication and Gene Expression Patterns of Feline Cells—Building a Better Understanding of Serotype I FIPV Biology

open access: yesViruses, 2022
Feline infectious peritonitis (FIP) is a disease of domestic cats caused by the genetic variant of the feline coronavirus (FCoV) and feline infectious peritonitis virus (FIPV), currently grouped into two serotypes, I and II.
Sarah Cook   +4 more
doaj   +1 more source

Suspect feline infectious peritonitis pada kucing [PDF]

open access: yes, 2018
Feline infectious peritonitis (FIP) adalah penyakit menular akibat infeksi corona virus dan dapat berakibat kematian. Diagnosa FIP dijumpai pada seekor kucing  dengan gejala anoreksia, lemas, perut membesar dan diare.
Widodo, Setyo   +11 more
core   +1 more source

Emerging Viruses in the Felidae: Shifting Paradigms

open access: yesViruses, 2012
The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning ...
Meredith A. Brown   +6 more
doaj   +1 more source

The emerging landscape of feline coronavirus type II in Asia: A review of molecular diversity and diagnostic challenges [PDF]

open access: yesBIO Web of Conferences
Feline infectious peritonitis (FIP) is a fatal systemic disease of cats caused by feline coronavirus (FCoV). FCoV is classified into two biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV).
Izofani Safira, Wasissa Madarina
doaj   +1 more source

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