Results 71 to 80 of about 1,407,592 (395)

Dynamic Hip Screw and Compression Plate Fixation of Ipsilateral Femoral Neck and Shaft Fractures

Journal of Orthopaedic Surgery, 2008
Purpose. To evaluate surgical outcomes of ipsilateral femoral neck and shaft fractures. Methods. Between April 1997 and September 2004, 29 men and 8 women (mean age, 37 years) underwent fixation of femoral neck and shaft fractures using a dynamic ...
A Abalo, A Dossim, AF Ouro Bangna, K Tomta, A Assiobo, A Walla   +5 more
doaj   +1 more source

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Bio-mechanical effects of femoral neck system versus cannulated screws on treating young patients with Pauwels type III femoral neck fractures: a finite element analysis

BMC Musculoskeletal Disorders
Introduction As a novel internal fixation for femoral neck fractures, the femoral neck system has some advantages for young Pauwels type III femoral neck fractures without clear biomechanical effects and mechanisms. Thus, the objection of the study is to
Xiao Fan, Yimin Zhou, Shiyou Dai, Kecheng Lao, Qiliang Zhang, Tengbo Yu   +5 more
doaj   +1 more source

Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]

, 2008
Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J., Maier, M., Milz, S., Pautke, C., Schmitz, C., Tischer, T., Weiler, C.   +6 more
core   +1 more source

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

Advanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni, Yufei Cui, Mojtaba Salehi, Mui Ling Sharon Nai, Kun Zhou, Cian Vyas, Boyang Huang, Paulo Bartolo   +7 more
wiley   +1 more source

Ground Truth Annotated Femoral X-Ray Image Dataset and Object Detection Based Method for Fracture Types Classification

IEEE Access, 2020
Precise classification of femoral fractures contributes to accurate surgical strategies and better prognosis after surgery. An effective and accurate system for diagnosing femoral fractures and classifying its types will play a vital role in clinical ...
Yubin Qi, Jing Zhao, Yongan Shi, Guilai Zuo, Haonan Zhang, Yuntao Long, Fan Wang, Wen Wang   +7 more
doaj   +1 more source

Intramedullary Nailing of Periarticular Fractures [PDF]

, 2018
Plate fixation has historically been the preferred surgical treatment method for periarticular fractures of the lower extremity. This trend has stemmed from difficulties with fracture reduction and concerns of inadequate fixation with intramedullary ...
Gaski, Greg, Kempton, Laurence, Sorkin, Anthony, Virkus, Walter   +3 more
core   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Femoral Neck Shaft Angle in Men with Fragility Fractures

Journal of Osteoporosis, 2011
Introduction. Femoral neck shaft angle (NSA) has been reported to be an independent predictor of hip fracture risk in men. We aimed to assess the role of NSA in UK men. Methods. The NSA was measured manually from the DXA scan printout in men with hip (62,
S. P. Tuck, D. J. Rawlings, A. C. Scane, I. Pande, G. D. Summers, A. D. Woolf, R. M. Francis   +6 more
doaj   +1 more source

The prevalence of fracture extension in displaced femoral neck fractures in the elderly

OTA International, 2019
. Objective:. Arthroplasty is the common treatment for intracapsular femoral neck fractures in the elderly. Recent studies have shown that there may be more overall complications related to uncemented hemiarthroplasty compared to cemented, including more
Kyle Matsuo Natsuhara, MD, Robert Downey Boutin, MD, Mark Andrew Lee, MD, John Patrick Meehan, MD   +3 more
doaj   +1 more source