Results 151 to 160 of about 5,495 (171)

Fenfluramine acts as a positive modulator of sigma-1 receptors

open access: yesEpilepsy and Behavior, 2020
OBJECTIVE: Adjunctive fenfluramine hydrochloride, classically described as acting pharmacologically through a serotonergic mechanism, has demonstrated a unique and robust clinical response profile with regard to its magnitude, consistency, and durability
Parthena Martin   +2 more
exaly   +2 more sources

p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in vivo

open access: yesPsychopharmacology, 1994
Previous work has suggested that repeated treatment with substituted amphetamines including PCA, MDMA and d-fenfluramine produces a persistent neurodegeneration which is relatively selective for the fine serotoninergic terminals arising from the dorsal ...
Philip Cowen, Trevor Sharp
exaly   +2 more sources

Successful use of fenfluramine as an add‐on treatment for Dravet syndrome

open access: yesEpilepsia, 2012
: Purpose: Despite the development of new antiepileptic drugs, Dravet syndrome frequently remains therapy resistant and is a catastrophic epilepsy syndrome.
Berten Ceulemans, Lieven Lagae
exaly   +1 more source

Hormonal Responses to d- and d,l-Fenfluramine in Healthy Human Subjects

Neuropsychopharmacology, 1996
Emil Coccaro   +2 more
exaly  

Effect of thymoleptics on fenfluramine-induced depletion of brain serotonin in rats

European Journal of Pharmacology, 1973
Vittorio Bertele', Rosario Samanin
exaly  

Biochemical pharmacology of the anorectic drug fenfluramine: a review

Current Medical Research and Opinion, 1979
Vittorio Bertele'   +2 more
exaly  

D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain

Brain Research, 1989
Lewis S Seiden, L S Seiden, M S Kleven
exaly  

Role of 5-HT receptors in the effect of d-fenfluramine on feeding patterns in the rat

European Journal of Pharmacology, 1992
Rosario Samanin, Giuliano Grignaschi
exaly  

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