Results 91 to 100 of about 29,324 (231)

Fenofibrate suppresses the progression of hepatoma by downregulating osteopontin through inhibiting the PI3K/AKT/Twist pathway [PDF]

, 2023
Weiqing Chen, Feihua Chen, Mouchun Gong, Lijun Ye, Dengcheng Weng, Zhaoqing Jin, Jianjiang Wang   +6 more
openalex   +1 more source

PPAR genomics and pharmacogenomics: Implications for cardiovascular disease [PDF]

, 2008
The peroxisome proliferator-activated receptors (PPARs) consist of three related transcription factors that serve to regulate a number of cellular processes that are central to cardiovascular health and disease.
Cresci, Sharon
core   +5 more sources

Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension

PPAR Research, 2011
Peroxisome proliferator-activated receptor-alpha (PPAR-α) activation by fenofibrate reduces blood pressure and sodium retention during DOCA-salt hypertension. PPAR-α activation reduces the expression of inflammatory cytokines, such as interleukin-6 (IL-
Dexter L. Lee, Justin L. Wilson, Rong Duan, Tamaro Hudson, Ahmed El-Marakby   +4 more
doaj   +1 more source

Fenofibrate prevents isoproterenol-induced left ventricular hypertrophy and pump dysfunction in rats [PDF]

, 2011
MSc (Med), University of the Witwatersrand, Faculty of Health Sciences, School of PhysiologyThe role of metabolic remodelling in heart failure is not fully understood, significant evidence has accumulated to suggest that it may be central to the ...
Maswanganyi, Tlangelani
core  

Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide

International Journal of Nanomedicine, 2012
Kwang-Ho Cha,1,3 Kyung-Jin Cho,3 Min-Soo Kim,4 Jeong-Soo Kim,3 Hee Jun Park,1,3 Junsung Park,1,3 Wonkyung Cho,1,3 Jeong-Sook Park,3 Sung-Joo Hwang1,21Yonsei Institute of Pharmaceutical Sciences, 2College of Pharmacy, Yonsei University, Incheon, Republic ...
Cha KH, Cho KJ, Kim MS, Kim JS, Park HJ, Park J, Cho W, Park JS, Hwang SJ   +8 more
doaj  

Cardiometabolic benefits of fenofibrate in heart failure related to obesity and diabetes

Cardiovascular Diabetology
Background Heart failure (HF) is a serious and common condition affecting millions of people worldwide, with obesity being a major cause of metabolic disorders such as diabetes and cardiovascular disease.
Jiwon Park, Hangyul Song, Shinje Moon, Yumin Kim, Sungsoo Cho, Kyungdo Han, Cheol-Young Park, Sung Woo Cho, Chang-Myung Oh   +8 more
doaj   +1 more source

Anti-hypertriglyceridemic Activity of Cornus Mas in Diabetic Rats [PDF]

, 2018
Introduction: Hypertriglyceridemia is among the multiple metabolic derangements seen in diabetes mellitus. Cornelian cherry (Cornus mas L.), belongs to the family Cornacea and has been shown to be helpful in treating hyperlipidemia.
Gholipour, Sajedeh., Rafieian-Kopaei, Mahmoud., Shomali, Tahoora.   +2 more
core  

An efficient analytic approach in genome-wide identification of methylation quantitative trait loci response to fenofibrate treatment [PDF]

, 2018
Jiayi W. Cox, Devanshi Patel, Jaeyoon Chung, Congcong Zhu, Samantha Lent, Virginia Fisher, Achilleas Pitsillides, Lindsay A. Farrer, Xiaoling Zhang   +8 more
openalex   +1 more source

PPARα Agonist Stimulated Angiogenesis by Improving Endothelial Precursor Cell Function Via a NLRP3 Inflammasome Pathway

Cellular Physiology and Biochemistry, 2017
Background: Impaired wound healing is a common complication of diabetes and is the leading cause of lower extremity amputation. Treatment with fenofibrate, a peroxisome proliferators–activated receptor α (PPARα) agonist, was associated with a lower risk ...
Yaping Deng, Xue Han, Zheng Yao, Yuannan Sun, Jiawen Yu, Jian Cai, Guofei Ren, Guojun Jiang, Feng Han   +8 more
doaj   +1 more source

LC—MS/MS Studies for the Identification and Characterization of Degradation Products of Fenofibrate and Their Degradation Pathways [PDF]

, 2015
Sugandha V. Mulgund, S. Anbazhegan, Satish Y. Gabhe   +2 more
openalex   +1 more source