Results 81 to 90 of about 16,301 (208)

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Fenofibrate-Induced Photosensitivity-a Case Report and Literature Review

open access: yes, 2011
Fenofibrate, a fibric acid derivative, is among the most commonly used antihyperlipidemic medications. Although variable kinds of cutaneous eruption occurred in about 2% of fenofibrate users, photosensitivity was assumed to be a rare manifestation ...
洪楨邦;王修含;朱家瑜   +1 more
core  

Cost-effectiveness of fenofibrate for preventing diabetic complications in Australia

open access: yes
BACKGROUND: This study investigated the cost-effectiveness of using fenofibrate to treat type 2 diabetes in Australia. The financial burden of type 2 diabetes mellitus is estimated to surpass AUD10 billion, mainly due to the cost of diabetic ...
Kim, H   +7 more
core   +1 more source

Effects of fenofibrate on bile lipid composition.

open access: yes, 1985
In humans, clofibrate increases the degree of bile cholesterol saturation and predisposes patients to cholesterol gallstone formation. To determine if this activity extends to the related hypolipidemic agent fenofibrate, duodenal bile lipid composition ...
R H Palmer
core   +1 more source

Microalgae Oil Attenuates Liver Fat Deposition in NAFLD via Modulation of Anti‐Lipogenic Genes and Insulin Signaling Pathways in HFD Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Dietary microalgae oil might reverse hepatic lipid deposition in a mouse model of fatty liver. This intervention significantly improves the overall fatty liver condition by reducing lipid accumulation and simultaneously restoring insulin sensitivity. ABSTRACT Non‐alcoholic fatty liver disease (NAFLD) is a leading cause of liver‐related mortality and ...
Athba AlQahtani   +8 more
wiley   +1 more source

Fenofibrate modified-release pellets with lag phase and high oral bioavailability

open access: yes, 2018
Fang Li,1,* Xin Zheng,2,* YongChu Bao,3 Ting Chen,3 Jia Zeng,1 XiaoLi Xu,4 Chao Yan,5 LingLin Feng1 1NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, and Shanghai Engineer and ...
Zheng X   +7 more
core  

ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro

open access: yesMolecular Cancer, 2010
Background Glioblastomas are characterized by rapid cell growth, aggressive CNS infiltration, and are resistant to all known anticancer regimens. Recent studies indicate that fibrates and statins possess anticancer potential.
Del Valle Luis   +7 more
doaj   +1 more source

Effects of Egg White Powder Supplementation on Nutritional Status, Biochemical Profile, and Oxidative Stress Markers in Diabetic Hemodialysis Patients; A Double‐Blind Randomized Controlled Trial

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Protein‐energy wasting (PEW) and oxidative stress (OS) frequently occur as complications in patients undergoing hemodialysis (HD), especially among those diagnosed with type 2 diabetes mellitus (T2DM). Egg white powder (EWP) is a low‐phosphorus, high‐ biological value protein source that may help improve nutritional and ...
Arvin Babaei   +4 more
wiley   +1 more source

Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing

open access: yes, 2008
Michel FarnierPoint Médical, Dijon, FranceAbstract: Mixed dyslipidemia is a common lipid disorder characterized by the presence of an atherogenic lipoprotein phenotype due to abnormalities in various atherogenic and antiatherogenic lipoproteins ...
Michel Farnier
core  

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade   +5 more
wiley   +1 more source

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