Results 101 to 110 of about 16,301 (208)

Development of an oral push–pull osmotic pump of fenofibrate-loaded mesoporous silica nanoparticles

open access: yes, 2015
Zongzhe Zhao, Chao Wu, Ying Zhao, Yanna Hao, Ying Liu, Wenming ZhaoPharmacy School, Liaoning Medical University, Jinzhou, Liaoning Province, People’s Republic of ChinaAbstract: In this study, mesoporous silica nanoparticles (MSNs) were used to ...
Liu Y   +5 more
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Fenofibrate and Insulin Resistance

open access: yes, 2011
Both animal and human models suggest that fenofibrate, a medication widely prescribed to decrease triglycerides, also decreases insulin resistance. In the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) cohort, which included 780 individual who
Paeglow, Corrie E
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Fenofibrate and left ventricle remodeling in volume overload

open access: yes, 2012
Aims : Fenofibrate is a peroxisome proliferator-associated receptor alpha agonist (PPARα) used clinically for the management of dyslipidemia and is a myocardial fatty acid oxidation stimulator.
Roussel, Élise   +4 more
core   +1 more source

The role of fenofibrate in clinical practice.

open access: yes, 2007
Clinical guidelines highlight the importance of dyslipidaemia management for reducing the risk of cardiovascular disease in patients with type 2 diabetes and metabolic syndrome.
Cusi K.   +3 more
core   +1 more source

Fenofibrate ameliorated atorvastatin and piperine-induced ROS mediated reproductive toxicity in male Wistar rats

open access: yesToxicology Reports
Atorvastatin and fenofibrate are well-known lipid-lowering drugs. Atorvastatin acts by reducing the production of cholesterol through the inhibition of the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG Co-A reductase) enzyme, whereas fenofibrate ...
Sanjib Ghosh   +2 more
doaj   +1 more source

Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension

open access: yesPPAR Research, 2011
Peroxisome proliferator-activated receptor-alpha (PPAR-α) activation by fenofibrate reduces blood pressure and sodium retention during DOCA-salt hypertension. PPAR-α activation reduces the expression of inflammatory cytokines, such as interleukin-6 (IL-
Dexter L. Lee   +4 more
doaj   +1 more source

Short Reports - Fenofibrate-induced myopathy

open access: yes, 2004
Fenofibrate induced myopathy is a rare adverse event. We present a case of muscle pain and quadriparesis following administration of 200mg of fenofibrate for 35 days. Patient gradually improved after stopping the drug.
Bhaskar Ghosh   +4 more
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Dose-dependent effects of fenofibrate and uridine.

open access: yes, 2014
(A) CARS images of liver tissues of C57bl/6 mice treated with different fenofibrate dosages. (B) Quantitative analysis of liver lipid level using ImageJ-assisted analysis of CARS images.
Thuc T. Le (114801)   +2 more
core   +1 more source

Fenofibrate attenuates the massive inflammatory response seen in JEV infection.

open access: yes, 2013
The inflammatory response to JEV challenge was attenuated by fenofibrate as depicted by significant reduction in mRNA expression (A) and protein levels (B) of cytokines (TNF-α, IL-6, IL-1β) and chemokine (MCP-1) compared to JEV alone.
Kanhaiya Lal Kumawat (102188)   +3 more
core   +1 more source

Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis

open access: yes, 2015
Yan Zhang,1,2,* Sainan Li,1,* Lei He,1 Fan Wang,1 Kan Chen,1 Jingjing Li,1 Tong Liu,1 Yuanyuan Zheng,1 Jianrong Wang,1,3 Wenxia Lu,1,3 Yuqing Zhou,1,4 Qin Yin,1,4 Yujing Xia,1 Yingqun Zhou,1 Jie Lu,1 Chuanyong Guo1 1Department of Gastroenterology ...
Xia Y   +14 more
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