Results 101 to 110 of about 25,748 (208)

Preparation And Evaluation Of Fenofibrate-Gelucire 44/14 Solid Dispersions [PDF]

, 2007
Potensi formulasi berasaskan sebaran pepejal menggunapakai Gelucire 44/14 sebagai pembawa untuk meningkatkan pelarutan serta biokeperolehan oral fenofibrat, sejenis drug yang tak mudah larut, telah disiasat.
Al-Dhalli, Samer
core   +1 more source

PPARα Agonist Stimulated Angiogenesis by Improving Endothelial Precursor Cell Function Via a NLRP3 Inflammasome Pathway

Cellular Physiology and Biochemistry, 2017
Background: Impaired wound healing is a common complication of diabetes and is the leading cause of lower extremity amputation. Treatment with fenofibrate, a peroxisome proliferators–activated receptor α (PPARα) agonist, was associated with a lower risk ...
Yaping Deng, Xue Han, Zheng Yao, Yuannan Sun, Jiawen Yu, Jian Cai, Guofei Ren, Guojun Jiang, Feng Han   +8 more
doaj   +1 more source

Cardiometabolic benefits of fenofibrate in heart failure related to obesity and diabetes

Cardiovascular Diabetology
Background Heart failure (HF) is a serious and common condition affecting millions of people worldwide, with obesity being a major cause of metabolic disorders such as diabetes and cardiovascular disease.
Jiwon Park, Hangyul Song, Shinje Moon, Yumin Kim, Sungsoo Cho, Kyungdo Han, Cheol-Young Park, Sung Woo Cho, Chang-Myung Oh   +8 more
doaj   +1 more source

Fenofibrate ameliorated atorvastatin and piperine-induced ROS mediated reproductive toxicity in male Wistar rats

Toxicology Reports
Atorvastatin and fenofibrate are well-known lipid-lowering drugs. Atorvastatin acts by reducing the production of cholesterol through the inhibition of the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG Co-A reductase) enzyme, whereas fenofibrate ...
Sanjib Ghosh, Sweata Sarkar, Maharaj Biswas   +2 more
doaj   +1 more source

Fenofibrate prevents isoproterenol-induced left ventricular hypertrophy and pump dysfunction in rats [PDF]

, 2011
MSc (Med), University of the Witwatersrand, Faculty of Health Sciences, School of PhysiologyThe role of metabolic remodelling in heart failure is not fully understood, significant evidence has accumulated to suggest that it may be central to the ...
Maswanganyi, Tlangelani
core  

Anti-hypertriglyceridemic Activity of Cornus Mas in Diabetic Rats [PDF]

, 2018
Introduction: Hypertriglyceridemia is among the multiple metabolic derangements seen in diabetes mellitus. Cornelian cherry (Cornus mas L.), belongs to the family Cornacea and has been shown to be helpful in treating hyperlipidemia.
Gholipour, Sajedeh., Rafieian-Kopaei, Mahmoud., Shomali, Tahoora.   +2 more
core  

Fenofibrate targets PPARα-CPT1C axis to reverse aging by regulating lipid metabolism and mitochondrial function

Pharmacological Research
Aging poses a growing global health burden, creating an urgent need for effective interventions. This study reveals that fenofibrate, a clinically approved drug for hyperlipidemia, exerts significant anti-aging effects by targeting fundamental aging ...
Yanying Zhou, Yixin Chen, Linlin Zhu, Huilin Li, Yue Gao, Tu Xian, Pengfei Zhao, Shicheng Fan, Núria Casals, Min Huang, Huichang Bi   +10 more
doaj   +1 more source

Cost-effectiveness of fenofibrate for preventing diabetic complications in Australia

Cost Effectiveness and Resource Allocation
Background This study investigated the cost-effectiveness of using fenofibrate to treat type 2 diabetes in Australia. The financial burden of type 2 diabetes mellitus is estimated to surpass AUD10 billion, mainly due to the cost of diabetic complications
Hansoo Kim, Juntao Lyu, Vikrama Raja, Kyoo Kim   +3 more
doaj   +1 more source

Effects of 'Authorized-Generics' on Canadian Drug Prices [PDF]

This paper examines how the use of ‘authorized-generics’ (AGs) influences Canadian prescription drug prices. An authorized-generic is the actual brand name drug product, manufactured by the brand firm, but sold as a generic by a licensee or subsidiary of
Paul Grootendorst
core  

Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia. [PDF]

RSC Med Chem
Holt-Martyn JP, Machado N, Coates JTT, Puliyadi R, Ashton T, Traynor E, Aslam S, Wise TK, Rodriguez-Berriguete G, Schofield CJ, Higgins GS.   +10 more
europepmc   +1 more source