Results 61 to 70 of about 13,138 (168)
ABSTRACT A 44‐year‐old man presented with acute abdominal pain and was diagnosed with hypertriglyceridemia‐induced acute pancreatitis. He was managed with fluid resuscitation, analgesia, and insulin infusion and had good recovery. Recognizing hypertriglyceridemia as an etiology of acute pancreatitis and insulin infusion as a treatment modality is ...
Mukti Nath Sankhi +5 more
wiley +1 more source
Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential
Anticancer effects of a common lipid-lowering drug, fenofibrate, have been described in the literature for a quite some time; however, fenofibrate has not been used as a direct anticancer therapy.
J. Stalinska +15 more
doaj +1 more source
Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu +6 more
wiley +1 more source
Robust HPLC method quantifies four antihyperlipidemic drugs. Central composite design optimized the analytical conditions. Achieved complete isocratic separation in under 10 min. Multiple green metrics confirmed excellent environmental sustainability. Validated method successfully analyzed commercial binary formulations.
Venkatesh Bukkapatnam, Raja Sundararajan
wiley +1 more source
Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro
Uncontrolled activity of T cells mediates autoimmune and inflammatory diseases such as multiple sclerosis, inflammatory bowel diseases, rheumatoid arthritis, type 1 diabetes, and atherosclerosis.
Zhou Zhou +7 more
doaj +1 more source
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Kwang-Ho Cha,1,3 Kyung-Jin Cho,3 Min-Soo Kim,4 Jeong-Soo Kim,3 Hee Jun Park,1,3 Junsung Park,1,3 Wonkyung Cho,1,3 Jeong-Sook Park,3 Sung-Joo Hwang1,21Yonsei Institute of Pharmaceutical Sciences, 2College of Pharmacy, Yonsei University, Incheon, Republic ...
Cha KH +8 more
doaj
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source
Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is widely prescribed for hyperlipidemia management. Recent studies also showed that it has therapeutic potential in various liver diseases.
Shicheng Fan +11 more
doaj +1 more source
Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study[S]
Hypertriglyceridemia, defined as a triglyceride measurement > 150 mg/dl, occurs in up to 34% of adults. Fenofibrate is a commonly used drug to treat hypertriglyceridemia, but response to fenofibrate varies considerably among individuals.
Mary K. Wojczynski +8 more
doaj +1 more source

