Results 111 to 120 of about 195,889 (397)

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.
Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick R. Labelle, Nancy Poole, Nicole Racine   +6 more
wiley   +1 more source

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance in male and female mice

Addiction Neuroscience
The number of opioid overdose deaths has increased over the past several years, mainly driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the un-regulated drug supply.
Anthony M. Downs, Gracianne Kmiec, Zoé A. McElligott   +2 more
doaj   +1 more source

Butorphanol for Post-Operative Analgesia - A Comparative Clinical Study with Ketorolac [PDF]

, 2010
Introduction: Butorphanol, an opioid derivative has been shown to have, in addition to its analgesic properties, several other advantageous effects like antistressor, sedative and anti-shivering action.
Adappa, Karunakara, Kadam, Dinesh, Kadri, Rajani, Koteshwar, Reshma, Mohan, Prashanth, Shenoy, Sunil P, Tantry, Thrivikrama Padur, Vastrad, Nandish S   +7 more
core   +1 more source

Ion Chemistry in Dielectric Barrier Discharge Ionization: Recent Advances in Direct Gas Phase Analyses

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Dielectric barrier discharge ionization (DBDI) sources, employing low‐temperature plasma, have emerged as sensitive and efficient ionization tools with various atmospheric pressure ionization processes. In this review, we summarize a historical overview of the development of DBDI, highlighting key principles of gas‐phase ion chemistry and the ...
Kseniya Dryahina, Miroslav Polášek, Juraj Jašík, Kristýna Sovová, Patrik Španěl   +4 more
wiley   +1 more source

Intraoperative fentanyl in endoscopic procedures and their impact on PACU time and costs

Perioperative Medicine
Background Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and financial implications in outpatient ...
Miho Akabane, Kelsey Kukuruza, Timothy Angelotti, Subhas Banerjee, Kazuo Ando   +4 more
doaj   +1 more source

Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone

Toxics
Opioid-related deaths are attributed to overdoses, and fentanyl overdose has been on the rise in many parts of the world, including the USA. Glutamate transporter 1 (GLT-1) has been identified as a therapeutic target in several preclinical models of ...
Mohammed S. Alasmari, Fawaz Alasmari, Shakir D. Alsharari, Abdullah F. Alasmari, Nemat Ali, Syed Rizwan Ahamad, Abdullah M. Alghamdi, Aban A. Kadi, Alaa M. Hammad, Yousif S. Mohamed Ali, Wayne E. Childers, Magid Abou-Gharbia, Youssef Sari   +12 more
doaj   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source

Illicit drug use and cerebral microbleeds in stroke and transient ischemic attack patients [PDF]

, 2019
Background: Cerebral microbleeds (CMB) signal cerebral small vessel disease and are associated with ischemic stroke (IS) incidence, recurrence, and complications.
Abbas, Saleh, Aparicio, Hugo, Cajiga-Pena, Fe Maria, Cervantes-Arslanian, Anna, Dam, Katie, Finn, Brandon, Greer, David, Lau, Helena, Nguyen, Thanh, Petrie, Benjamin, Romero, Jose Rafael   +10 more
core   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source