Results 171 to 180 of about 72,009 (260)

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Anesthetic Management in Patients with Impella Devices: A Retrospective Review and Clinical Guide. [PDF]

Ann Card Anaesth
Yang H, Gouda D, Berg KB, Green K, Sundaresh S, Goudra B.   +5 more
europepmc   +1 more source

On the adaptive significance of group III/IV muscle afferent feedback for the cardiovascular response during sustained locomotion in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Group III/IV leg muscle afferent feedback has previously been recognized as an important determinant of the cardiovascular response to exercise lasting <5 min. Here we demonstrate that the activity of these neurons is crucial in regulating central and peripheral haemodynamic responses during steady state exercise of longer ...
D. Iannetta, F. G. Laginestra, T. S. Thurston, R. H. Jenkinson, J. Chang, H.‐Y. Wan, R. M. Broxterman, J. C. Weavil, M. Amann   +8 more
wiley   +1 more source

Naloxone Administration in Relation to Fentanyl, Xylazine, CNS Depressants, and Stimulants Exposure After Suspected Opioid Overdose: A Pilot Study. [PDF]

Acad Emerg Med
Merchant RC, Chapman B, Martinez PM, Krotulski A, Walton S, Carmen Vargas-Torres, Broach J, Babu KM.   +7 more
europepmc   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Effects of Infraorbital Nerve Block with Dexmedetomidine-Added Bupivacaine on Intraoperative Opioid Consumption and Postoperative Analgesia During Endoscopic Transsphenoidal Surgery: A Prospective, Randomized, Double-Blind Controlled Trial. [PDF]

J Pain Res
Phothikun N, Pinon P, Saringkarinkul A, Polperm T, Plubnim N, Phothikun A.   +5 more
europepmc   +1 more source

Experimental Investigation of Fentanyl Analgesic Potency and Its Relationship with Endogenous Adrenaline Levels in Rats. [PDF]

J Pain Res
Ates I, Isik B, Sezgin ET, Altuner D, Coban TA, Suleyman H.   +5 more
europepmc   +1 more source

Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiety while improving patient acceptance and procedural quality. In Japan, benzodiazepines such as midazolam and opioid analgesics have long been widely used in routine clinical practice; however, many of these agents historically
Ryoji Ichijima, Masahiro Toyama, Taiki Shishido, Yuki Koyo, Takehiro Yoshii, Reona Kawamura, Tsubasa Ishikawa, Yasuhiko Mizuguchi, Naoya Toyoshima, Hiroyuki Takamaru, Masayoshi Yamada, Masau Sekiguchi, Seiichiro Abe, Yutaka Saito   +13 more
wiley   +1 more source

Antinociceptive Effect and Hyperalgesia of Fentanyl and Its Analogues. [PDF]

Int J Mol Sci
Chen Y, Li K, Li X, Zhang S, Xu D, Xu Y, Qiao Y, Xu Y, Xia M, Qin W, Di B, Xu P.   +11 more
europepmc   +1 more source

Postoperative Effects of Celecoxib on Opioid Use and Pain Control After Benign Oropharyngeal Surgery

The Laryngoscope, Volume 136, Issue 9, Page 4072-4080, September 2026.
This study evaluated how the addition of celecoxib to a multimodal pain regimen following tonsillectomy + adenoidectomy, or uvulopalatopharyngoplasty (UPPP) + tonsillectomy affects postoperative opioid use and pain control. Patients who received celecoxib consumed significantly fewer opioids compared to the historic control group, with similar ...
Alana Platukus, Praneet Kaki, Anastasia Kaffenes, Udeerna Tippabhatla, Jared Robinson, Jaehee Kim, Erin Creighton, Meghan Crippen, Maurits Boon, Colin Huntley   +9 more
wiley   +1 more source