Results 181 to 190 of about 72,009 (260)

Occupational exposures to illicit drugs in forensic science divisions. [PDF]

J Occup Environ Hyg
Cox J, Bartels J, Niang M, Li J, Broadwater K, Chiu S, Shi D, Sen P, Chen IC, Gerona R, Gonzaga M, Dahm M.   +11 more
europepmc   +1 more source

The rs10781468 Genetic Polymorphism of the Gαq (GNAQ) Gene Is Associated With Responsiveness to Opioid Analgesics in Patients With Postoperative and Cancer Pain: An Exploratory Study

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
In our exploratory hypothesis‐generating study using patients with postoperative pain and cancer pain, for rs10781468 in the GNAQ gene, the minor allele was associated with reduced opioid consumption and an increased pain threshold. ABSTRACT Background G protein–coupled receptors, the largest class of cell surface receptors, are ubiquitously expressed ...
Hiroaki Owada, Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Rikuhei Tsuchida, Yaeko Yokoshima, Akira Kitamura, Masakazu Hayashida, Ken‐ichi Fukuda, Tatsuya Ichinohe, Kazutaka Ikeda, Makoto Kurano, Masahiko Sumitani, Kanji Uchida   +15 more
wiley   +1 more source

Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice. [PDF]

Psychopharmacology (Berl)
Watkins JM, Hahn R, Dempsey M, Hohmann AG.   +3 more
europepmc   +1 more source

Impact of Institutional Protocol on Urinary Catheter Outcome Measures in Orthopedic Children Treated With Epidural Analgesia

Pediatric Anesthesia, Volume 36, Issue 9, Page 1089-1095, September 2026.
ABSTRACT Background Epidural analgesia is commonly used for pain control after major lower‐limb orthopedic surgery in children, but it is associated with a risk of postoperative urinary retention. Consequently, urinary catheters are often placed and left in situ for the full duration of epidural analgesia, despite the potential risks of prolonged ...
Idan Katz, Tomer Talmy, Dor Barami, Tal S. Beckmann, Barry Danino, Yotam Lior, Margaret Ekstein   +6 more
wiley   +1 more source

G protein regulatory network shapes magnitude and kinetics of behavioral responses in an engineered opioid receptor model. [PDF]

J Biol Chem
Coleman DL, Ren RJ, Opperman KJ, Kwan EX, Martemyanov KA, Grill B.   +5 more
europepmc   +1 more source

Processed EEG Monitoring During Pediatric Procedural Sedation: Correlation Between the Narcotrend Index and the Pediatric Sedation State Scale

Pediatric Anesthesia, Volume 36, Issue 9, Page 1126-1131, September 2026.
ABSTRACT Background Objective assessment of sedation depth in children undergoing procedural sedation while maintaining spontaneous breathing and protective reflexes can be challenging. Processed electroencephalogram (pEEG) monitoring systems such as the Narcotrend monitor may provide continuous information regarding the depth of sedation.
Hendryk Schneider, Daniel Matheisl, Martin Kuntz, Hans Fuchs   +3 more
wiley   +1 more source

Feasibility of a Modified Wake-Up Test Without Intraoperative Neurophysiological Monitoring in Scoliosis Surgery: A Case Series. [PDF]

Case Rep Anesthesiol
D Ta L, V Nguyen H, V Vu C, Lam DT.
europepmc   +1 more source

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, Volume 36, Issue 9, Page 1132-1142, September 2026.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase. [PDF]

Drugs Real World Outcomes
Suh B, Oh HS, Shin JY, Kim JH.
europepmc   +1 more source

Effects of Topical Administration of Bupivacaine HCl to the Ovarian Pedicle on Postoperative Pain, Antioxidant Enzyme Activity and Inflammatory Cytokines in Dogs Undergoing Laparoscopic Ovariectomy

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Topical bupivacaine HCl applied to the ovarian pedicle during laparoscopic ovariectomy in dogs significantly reduced early postoperative UMPS pain scores and modulated antioxidant enzyme activity (SOD, CAT). However, systemic pro‐inflammatory cytokine levels (IL‐1β, IL‐6 and TNF‐α) remained unchanged between groups.
Alper Yasin Çiplak, Bülent Polat
wiley   +1 more source