Results 41 to 50 of about 195,889 (397)
PHARMACOKINETICS OF FENTANYL IN THE ELDERLY [PDF]
Anesthesiology, 1985 The pharmacokinetics of fentanyl were determined in seven elderly (71-82 yr) and seven younger adults (18-41 yr) anaesthetized with thiopentone, nitrous oxide in oxygen and morphine. Fentanyl was administered as a 2-min i.v. infusion at doses of 15 micrograms kg-1 for elderly patients and 20 micrograms kg-1 for the younger patients. Plasma samples were
M A Singleton +2 more
openaire +5 more sources
The Fentanyl Epidemic and Evolution of Fentanyl Analogs in the United States and the European Union.
Clinical Chemistry, 2019 BACKGROUND Since 2013, an unprecedented surge in fentanyl overdose deaths has been caused by heroin laced with illicitly produced fentanyl and/or fentanyl analogs (FAs) sold as heroin.
P. Jannetto +5 more
semanticscholar +1 more source
Recent Changes in Drug Abuse Scenario: The Novel Psychoactive Substances (NPS) Phenomenon [PDF]
, 2019 copyright 2019 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are ...
Catalani, Valeria +7 more
core +3 more sources
Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]
, 2018 While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover +8 more
core +2 more sources
Fentanyl for labour pain management: a scoping review
BMC Pregnancy and Childbirth, 2022 Background Labour pain has been identified as an important reason for women to prefer caesarean section (CS). Fentanyl is one of the short acting opioids recommended by World Health Organization for pain relief during labour. This study aimed to identify
Kyaw Lwin Show +9 more
doaj +1 more source
Nigerian Postgraduate Medical Journal, 2022 Background: Insertion of laryngeal mask airway (LMA) with propofol in children may cause hypotension, laryngospasm and apnoea. Ketamine and fentanyl have been combined separately with propofol to prevent depression of cardiovascular system during LMA ...
Ajibade Okeyemi +5 more
doaj +1 more source
Harm Reduction Journal, 2019 BackgroundIn 2016, drug overdose deaths exceeded 64,000 in the United States, driven by a sixfold increase in deaths attributable to illicitly manufactured fentanyl.
Jacqueline E. Goldman +5 more
semanticscholar +1 more source
The challenge of perioperative pain management in opioid-tolerant patients [PDF]
, 2017 The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F +9 more
core +6 more sources
Effects of chronic fentanyl administration on behavioral characteristics of mice
Neuropsychopharmacology Reports, 2019 Background Fentanyl, a synthetic opioid categorized as a narcotic analgesic, has a 100‐ to 200‐fold stronger effect than most opioids, such as morphine. Fatal accidents due to chronic use and abuse of fentanyl are a worldwide social problem.
Kazuki Fujii +3 more
doaj +1 more source
Investigation of monoclonal antibody CSX-1004 for fentanyl overdose
Nature Communications, 2023 The opioid crisis in the United States is primarily driven by the highly potent synthetic opioid fentanyl leading to >70,000 overdose deaths annually; thus, new therapies for fentanyl overdose are urgently needed. Here, we present the first clinic-ready,
Paul T. Bremer +3 more
doaj +1 more source