Results 41 to 50 of about 87,565 (266)

Pre-induction fentanyl dose-finding study for controlled hypotension during functional endoscopic sinus surgery

Indian Journal of Anaesthesia, 2019
Background and Aims: Fentanyl can facilitate controlled intraoperative hypotension by its sympatholytic effect in patients undergoing functional endoscopic sinus surgery (FESS).
Prabhat Choudhary, Amitabh Dutta, Nitin Sethi, Jayashree Sood, Devinder Rai, Manish Gupta   +5 more
doaj   +1 more source

Dose- and Sex-Dependent Bidirectional Relationship between Intravenous Fentanyl Self-Administration and Gut Microbiota

Microorganisms, 2022
Gut bacteria influence neural circuits in addiction-related behaviors. Given the association between opioid use, gastrointestinal distress, and microbial dysbiosis in humans and mice, we test the hypothesis that interactions between gut bacteria and the ...
Michelle Ren, Shahrdad Lotfipour
doaj   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Rasquache vulnerability and theories of the flesh: Working through the flesh in (auto)ethnography as a site of disruption

Feminist Anthropology, EarlyView.
Abstract In this article, I blend authoethnography and ethnography to activate a Chicanx feminist theory of the flesh, which is grounded in the sensibilities of vulnerability and rasquachismo. Rasquachismo is a politicized Mexican American visceral modality of being in the world—in art, in politics, in everydayness—that is rooted in purposeful defiance
Andrea M. Lopez
wiley   +1 more source

Fentanyl and its derivatives: Pain-killers or man-killers?

Heliyon
Fentanyl is a synthetic μ-opioid receptor agonist approved to treat severe to moderate pain with faster onset of action and about 100 times more potent than morphine.
Jiri Patocka, Wenda Wu, Patrik Oleksak, Romana Jelinkova, Eugenie Nepovimova, Lenka Spicanova, Pavlina Springerova, Suliman Alomar, Miao Long, Kamil Kuca   +9 more
doaj   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Evaluating fentanyl test strips as a harm reduction strategy in rural and urban counties: study protocol for a randomized controlled trial

Trials
Background Opioid-related fatalities are a leading cause of death in Ohio and nationally, with an increasing number of overdoses attributable to fentanyl. Rapid fentanyl test strips can identify fentanyl and some fentanyl analogs in urine samples and are
Ashley Short Mejia, Gary A. Smith, Soledad A. Fernandez, Bridget Freisthler, Christine Grella, Nichole L. Michaels   +5 more
doaj   +1 more source

Clinical and Financial Impact of Addiction Medicine Pharmacy Specialist

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
ABSTRACT Background Pain management in patients with substance use disorder (SUD) is complex and often under‐addressed in inpatient settings. Clinical pharmacy specialists (CPS) with expertise in pain management and addiction medicine can play a critical role in closing this care gap. To quantify and describe the clinical and financial impact of a Pain
Emily R. Casey, Jacob Radcliff, Tanya J. Uritsky   +2 more
wiley   +1 more source

Fentanyl, carfentanil and other fentanyl analogues in Canada’s illicit opioid supply: A cross-sectional study

Drug and Alcohol Dependence Reports
Background: Despite the increase in fentanyl-involved overdose deaths in Canada, there have been no national-level studies evaluating the proportion of illicit opioids containing fentanyl or fentanyl analogues in Canada.
Robert A. Kleinman
doaj   +1 more source