Results 101 to 110 of about 1,032,017 (343)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
AMB Express, 2017 Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an
SooJin Han +5 more
doaj +1 more source
A model for pH determination during alcoholic fermentation of a grape must by Saccharomyces cerevisiae [PDF]
, 2008 A model to predict accurately pH evolution during alcoholic fermentation of must by Saccharomyces cerevisiae is proposed for the first time. The objective at least is to determine if the pH measurement could be used for predictive control.
Akin, Huberson +3 more
core +1 more source
FEBS Open Bio, EarlyView.Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto +5 more
wiley +1 more source
Soft Sensor Modeling Method for the Marine Lysozyme Fermentation Process Based on ISOA-GPR Weighted Ensemble Learning [PDF]
, 2023 Na Lü, Bo Wang, Xianglin Zhu
openalex +1 more source
Fermentation of plant-based milk alternatives for improved flavour and nutritional value
Applied Microbiology and Biotechnology, 2019 Non-dairy milk alternatives (or milk analogues) are water extracts of plants and have become increasingly popular for human nutrition. Over the years, the global market for these products has become a multi-billion dollar business and will reach a value ...
M. Tangyu +3 more
semanticscholar +1 more source
125th anniversary review: fuel alcohol: current production and future challenges [PDF]
, 2011 Global research and industrial development of liquid transportation biofuels are moving at a rapid pace. This is mainly due to the significant roles played by biofuels in decarbonising our future energy needs, since they act to mitigate the deleterious ...
Walker, Graeme M.
core +3 more sources
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
The design of unit cells by combining the self-reproduction systems and metabolic cushioning loads
Communications BiologyRecently, we published a comprehensive theoretical analysis of the self-reproduction processes in proto-cells (doubling of their components) composed of different combinations of cellular subsystems.
Kristo Abner +8 more
doaj +1 more source
Influences of Lactate on the High-density Fermentation by Bacillus licheniformis HK
Shipin gongye ke-jiTo improve the biomass and spore rate of Bacillus licheniformis HK, influences of lactate on cell growth and metabolism and spore production were investigated at a 20 L bioreactor, and lactate addition was conducted by coupling with pH7.0 from 16 h to 32
Yanmei ZHAO +6 more
doaj +1 more source