Impact of <i>Lactiplantibacillus plantarum</i> on the fermentation quality, nutritional enhancement, and microbial dynamics of whole plant soybean silage. [PDF]
Meng H +10 more
europepmc +1 more source
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
Improving fermentation quality, aerobic stability, and microbial community stabilization of triticale by <i>Amomum villosum</i> essential oil. [PDF]
Li M +12 more
europepmc +1 more source
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
Synergistic effects of <i>Lactiplantibacillus plantarum</i> and <i>Acacia mangium</i> leaf tannin extract on the fermentation quality, digestibility, and metabolomic profile of <i>Indigofera</i> silage. [PDF]
Azzahra FR +9 more
europepmc +1 more source
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li +15 more
wiley +1 more source
Effects of <i>Lactobacillus brevis</i> additives on nutrient composition, fermentation quality, microflora structure and metabolites of <i>Pennisetum giganteum</i> silage. [PDF]
Liao J +7 more
europepmc +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source
High temperatures and antibacterial plant additives change the fermentation quality, free amino acids and lactic acid bacteria fermentation type in Caragana Korshinskii silage. [PDF]
Zhou T +8 more
europepmc +1 more source
Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian +12 more
wiley +1 more source

